CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033774
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Profilin 
Protein Synonyms/Alias
  
Gene Name
 PFN2 
Gene Synonyms/Alias
 hCG_21343 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
327HGGTLNKKAYELALYubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 340 AA 
Protein Sequence
RGSKASVPPL FLGCRERRGV HPLRRPEVRS SARHRSRPAP PARGGRDCPG AVSLRAPASV 60
SPRPSRDPPC PGAAEGSHAR ARARPAVSAE NGGRCGKEQP PQAQPLRSLP PLVCQPRGCG 120
RPGGRARSEV RPSSLNPRPP AAAPRGGGRS VPAQSRLLPA PAPPPPAPPP PATAAAAAAP 180
AAPRRPRCSA KGSKMAGWQS YVDNLMCDGC CQEAAIVGYC DAKYVWAATA GGVFQSITPI 240
EIDMIVGKDR EGFFTNGLTL GAKKCSVIRD SLYVDGDCTM DIRTKSQGGE PTYNVAVGRA 300
GRVSLCTPAL VIVMGKEGVH GGTLNKKAYE LALYLRRSDV 340 
Gene Ontology
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR005454; Profilin_chordates.
 IPR005455; Profilin_eukaryotes/bac. 
Pfam
 PF00235; Profilin 
SMART
 SM00392; PROF 
PROSITE
  
PRINTS
 PR01639; PROFILINMAML.