CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039562
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Roundabout homolog 3 
Protein Synonyms/Alias
  
Gene Name
 ROBO3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1044DSGAKGGKVKLLGKPubiquitination[1]
1046GAKGGKVKLLGKPVQubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1364 AA 
Protein Sequence
MERPEDSLSL WSLNLSPQFP CLNALRHPLS PGSRVGPEDA MPRIVEQPPD LLVSRGEPAT 60
LPCRAEGRPR PNIEWYKNGA RVATVREDPR AHRLLLPSGA LFFPRIVHGR RARPDEGVYT 120
CVARNYLGAA ASRNASLEVA VLRDDFRQSP GNVVVAVGEP AVLECVPPRG HPEPSVSWRK 180
DGARLKEEEG RITIRGGKLM MSHTLKSDAG MYVCVASNMA GERESAAAEV MVLERPSFLR 240
RPVNQVVLAD APVTFLCEVK GDPPPRLRWR KEDGELPTGR YEIRSDHSLW IGHVSAEDEG 300
TYTCVAENSV GRAEASGSLS VHVPPQLVTQ PQDQMAAPGE SVAFQCETKG NPPPAIFWQK 360
EGSQVLLFPS QSLQPTGRFS VSPRGQLNIT AVQRGDAGYY VCQAVSVAGS ILAKALLEIK 420
GASLDGLPPV ILQGPANQTL VLGSSVWLPC RVTGNPQPSV RWKKDGQWLQ GDDLQFKTMA 480
NGTLYIANVQ EMDMGFYSCV AKSSTGEATW SGWLKMREDW GVSPDPPTEP SSPPGAPSQP 540
VVTEITKNSI TLTWKPNPQT GAAVTSYVIE AFSPAAGNTW RTVADGVQLE THTVSGLQPN 600
TIYLFLVRAV GAWGLSEPSP VSEPVRTQDS SPSRPVEDPW RGQQGLAEVA VRLQEPIVLG 660
PRTLQVSWTV DGPVQLVQGF RVSWRVAGPE GGSWTMLDLQ SPSQQSTVLR GLPPGTQIQI 720
KVQAQGQEGL GAESLSVTRS IPEEAPSGPP QGVAVALGGD GNSSITVSWE PPLPSQQNGV 780
ITEYQIWCLG NESRFHLNRS AAGWARSAML RGLVPGLLYR TLVAAATSAG VGVPSAPVLV 840
QLPSPPDLEP GLEVGAGLAV RLARVLREPA FLAGSGAACG ALLLGLCAAL YWRRKQRKEL 900
SHYTASFAYT PAVSFPHSEG LSGASSRPPM GLGPAPYSWL ADSWPHPSRS PSAQEPRGSC 960
CPSNPDPDDR YYNEAGISLY LAQTARGTAA PGEGPVYSTI DPAGEELQTF HGGFPQHPSG 1020
DLGPWSQYAP PEWSQGDSGA KGGKVKLLGK PVQMPSLNWP EALPPPPPSC ELSCLEGPEE 1080
ELEGSSEPEE WCPPMPERSH LTEPSSSGGC LVTPSRRETP SPTPSYGQQS TATLTPSPPD 1140
PPQPPTDMPH LHQMPRRVPL GPSSPLSVSQ PMLGIREARP AGLGAGPAAS PHLSPSPAPS 1200
TASSAPGRTW QGNGEMTPPL QGPRARFRKK PKALPYRREN SPGDLPPPPL PPPEEEASWA 1260
LELRAAGSMS SLERERSGER KAVQAVPLAA QRVLHPDEEA WLPYSRPSFL SRGQGTSTCS 1320
TAGSNSSRGS SSSRGSRGPG RSRSRSQSRS QSQRPGQKRR EEPR 1364 
Gene Ontology
  
Interpro
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2. 
Pfam
 PF00041; fn3
 PF07679; I-set 
SMART
 SM00060; FN3
 SM00408; IGc2 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE 
PRINTS