| Tag | Content |
|---|
| CPLM ID | CPLM-008860 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutamate dehydrogenase, mitochondrial |
Protein Synonyms/Alias | GDH |
Gene Name | Gdh |
Gene Synonyms/Alias | Glud; CG5320 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 449 | SYGRLTFKYERESNY | acetylation | [1] | | 500 | TPSESFQKRISGASE | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | |
Sequence Annotation | NP_BIND 132 134 NAD (By similarity).
ACT_SITE 174 174 By similarity.
BINDING 138 138 Substrate (By similarity).
BINDING 162 162 Substrate (By similarity).
BINDING 167 167 NAD (By similarity).
BINDING 243 243 NAD (By similarity).
BINDING 257 257 GTP (By similarity).
BINDING 261 261 GTP (By similarity).
BINDING 310 310 GTP (By similarity).
BINDING 313 313 GTP (By similarity).
BINDING 430 430 Substrate (By similarity).
BINDING 436 436 NAD (By similarity).
BINDING 442 442 ADP (By similarity).
BINDING 521 521 ADP (By similarity). |
Keyword | Alternative splicing; ATP-binding; Complete proteome; GTP-binding; Mitochondrion; NAD; Nucleotide-binding; Oxidoreductase; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 562 AA |
Protein Sequence | MYHLKSLARQ GARRQQELAT LAKALPTAVM QSSRGYATEH QIPDRLKDVP TAKDPRFFDM 60
VEYFFHRGCQ IAEESLVDDM KGKLTRDEKK QKVKGILMLM QPCDHIIEIA FPLRRDAGNY 120
EMITGYRAQH STHKTPTKGG IRFSLDVSRD EVKALSALMT FKCACVDVPF GGAKAGLKIN 180
PKEYSEHELE KITRRFTLEL AKKGFIGPGV DVPAPDMGTG EREMSWIADT YAKTIGHLDI 240
NAHACVTGKP INQGGIHGRV SATGRGVFHG LENFINEANY MSQIGTTPGW GGKTFIVQGF 300
GNVGLHTTRY LTRAGATCIG VIEHDGTLYN PEGIDPKLLE DYKNEHGTIV GYQNAKPYEG 360
ENLMFEKCDI FIPAAVEKVI TSENANRIQA KIIAEAANGP TTPAADKILI DRNILVIPDL 420
YINAGGVTVS FFEWLKNLNH VSYGRLTFKY ERESNYHLLA SVQQSIERII NDESVQESLE 480
RRFGRVGGRI PVTPSESFQK RISGASEKDI VHSGLDYTME RSARAIMKTA MKYNLGLDLR 540
TAAYVNSIEK IFTTYRDAGL AF 562 |
Gene Ontology | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:FlyBase. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IDA:FlyBase. GO:0004353; F:glutamate dehydrogenase [NAD(P)+] activity; IDA:FlyBase. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0042802; F:identical protein binding; IDA:FlyBase. GO:0006536; P:glutamate metabolic process; IDA:FlyBase. GO:0006116; P:NADH oxidation; IDA:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |