CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038158
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone demethylase UTY 
Protein Synonyms/Alias
  
Gene Name
 Uty 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
389SALTSRIKFLQAQLCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1211 AA 
Protein Sequence
MKSYGLSLTT AALGNEEKKM AAEKARGEGE EGSFSLTVEE KKALCGLDSF FGFLTRCKDG 60
AKMKTLLNKA IHFYESLIVK AEGKVESDFF CQLGHFNLLL EDYSKALSSY QRYYSLQTDY 120
WKNAAFLYGL GLVYFYYNAF QWAIRAFQEV LYVDPNFCRA KEIHLRLGFM FKMNTDYESS 180
LKHFQLALID CNVCTLSSVE IQFHIAHLYE TQRKYHSAKA AYEQLLQIES LPSQVKATVL 240
QQLGWMHHNM DLIGDNTTKE RYAIQYLQKS LEEDPNSGQS WYFLGRCYSC IGKVQDAFVS 300
YRQSIDKSEA SADTWCSIGV LYQQQNQPMD ALQAYICAVQ LDHGHAAAWM DLGILYESCN 360
QPQDAIKCYL NAARSKSCNN TSALTSRIKF LQAQLCNLPQ SSLQNKTKLL PSIEEAWSLP 420
IPAELTSRQG AMNTAQQSVS DTWNSVQTAS HHSVQQKVYT QCFTAQKLQS FGKDQQPPFQ 480
TGSTRYLQAA STNDQNQNGN HTLPQNSKGD AQNHFLRIPT SEEQKIINFT KESKDSRSKS 540
LTSKTSRKDR DTSNICVNAK KHSNHIYQIS SVPISSLNNK ESVSPDLIIV DNPQLSVLVG 600
ETIDNVDHDI GTCDKVNNVH LAIHKKPDNL SASSPSSAIS TETLSLKLTE QTHIVTSFIS 660
PHSGLHTING EGHENLESSA SVNVGLRPRS QIIPSMSVSI YSSSTEVLKA CRSLGKNGLS 720
NGHILLDICP PPRPPTSPYP PLPKEKLNPP TPSIYLENKR DAFFPPLHQF CINPKNPVTV 780
IRGLAGALKL DLGLFSTKTL VEANNEHIVE VRTQLLQPAD ENWDPSGTKK IWRYENKSSH 840
TTIAKYAQYQ ACSFQESLRE ENERRTQVKD YSDNESTCSD NSGRRQKAPF KTIKCGINID 900
LSDNKKWKLQ LHELTKLPAF VRVVSAGNLL SHVGYTILGM NSVQLCMKVP GSRIPGHQEN 960
NNFCSVNINI GPGDCEWFVV PEDYWGVLND FCEKNNLNFL MSSWWPNLED LYEANVPVYR 1020
FIQRPGDLVW INAGTVHWVQ AIGWCNNITW NVGPLTAFQY KLAVERYEWN KLQSVKSVVP 1080
MVHLSWNMAR NIKVSDPKLF EMIKYCLLKI LKHCQTLREA LVAAGKEVLW HGRINDEPAP 1140
YCSICEVEVF NLLFVTNESN SQKTYIVHCQ NCARKTSGNL ENFVVLEQYK MEDLIQVYDQ 1200
FTLAPSLSSA S 1211 
Gene Ontology
 GO:0051864; F:histone demethylase activity (H3-K36 specific); IMP:MGI.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.
 GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:MGI.
 GO:0086003; P:cardiac muscle cell contraction; IMP:MGI.
 GO:0045184; P:establishment of protein localization; IDA:MGI.
 GO:0007507; P:heart development; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0031935; P:regulation of chromatin silencing; IMP:MGI. 
Interpro
 IPR003347; JmjC_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF02373; JmjC
 PF13181; TPR_8 
SMART
 SM00558; JmjC
 SM00028; TPR 
PROSITE
 PS51184; JMJC
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS