CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015439
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 562 
Protein Synonyms/Alias
  
Gene Name
 ZNF562 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
22PICPFEEKTKIGTMVubiquitination[1]
24CPFEEKTKIGTMVEDubiquitination[1]
177SIGQELSKFNPCGKVubiquitination[1]
291GEKSFECKECGRSFRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 41 120 KRAB.
 ZN_FING 176 198 C2H2-type 1; degenerate.
 ZN_FING 204 226 C2H2-type 2.
 ZN_FING 260 282 C2H2-type 3; degenerate.
 ZN_FING 288 310 C2H2-type 4.
 ZN_FING 316 338 C2H2-type 5.
 ZN_FING 344 366 C2H2-type 6.
 ZN_FING 372 394 C2H2-type 7.
 ZN_FING 400 422 C2H2-type 8.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 426 AA 
Protein Sequence
MSAFDMSHGF FPREPICPFE EKTKIGTMVE DHRSNSYQDS VTFDDVAVEF TPEEWALLDT 60
TQKYLYRDVM LENYMNLASV DFFFCLTSEW EIQPRTKRSS LQQGFLKNQI FTGIQMQTRS 120
YSGWKLCENC GEVFSEQFCL KTHMRAQNGG NTFEGNCYGK DSISVHKEAS IGQELSKFNP 180
CGKVFTLTPG LAVHLEILNG RQPYKCKECG KGFKYFASLD NHMGIHIGEK LCEFQECERA 240
ITTSSHLKQC VAVHTGKKSE KTKNCGKSFT NFSQLSAHAK THKGEKSFEC KECGRSFRNS 300
SSFNVHIQIH TGIKPHKCTE CGKAFTRSTH LTQHVRTHTG IKPYECKECG QAFTQYTGLA 360
IHIRNHTGEK PYQCKECGKA FNRSSTLTQH RRIHTGEKPY ECVECGKTFI TSSHRSKHLK 420
THSGER 426 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS