| Tag | Content |
|---|
| CPLM ID | CPLM-024371 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Calcium-binding mitochondrial carrier protein SCaMC-2 |
Protein Synonyms/Alias | Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 member 25 |
Gene Name | Slc25a25 |
Gene Synonyms/Alias | Kiaa1896; Scamc2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 361 | CARRILAKEGVAAFY | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity). |
Sequence Annotation | DOMAIN 47 80 EF-hand 1.
DOMAIN 78 113 EF-hand 2.
DOMAIN 114 149 EF-hand 3.
REPEAT 184 270 Solcar 1.
REPEAT 278 363 Solcar 2.
REPEAT 375 463 Solcar 3. |
Keyword | Alternative splicing; Calcium; Complete proteome; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 469 AA |
Protein Sequence | MLQTLWHFLS SFLPRAECQD SREGIDHGVR GTQAPARGDQ MSTFLGKQNG RAEATEKRPT 60
ILLVVGPAEQ FPKKIVQAGD KDLDGQLDFE EFVHYLQDHE KKLRLVFKSL DKKNDGRIDA 120
QEIMQSLRDL GVKISEQQAE KILKRIRTGH FWGPVTYMDK NGTMTIDWNE WRDYHLLHPV 180
ENIPEIILYW KHSTIFDVGE NLTVPDEFTV EERQTGMWWR HLVAGGGAGA VSRTCTAPLD 240
RLKVLMQVHA SRSNNMCIVG GFTQMIREGG AKSLWRGNGI NVLKIAPESA IKFMAYEQMK 300
RLVGSDQETL RIHERLVAGS LAGAIAQSSI YPMEVLKTRM ALRKTGQYSG MLDCARRILA 360
KEGVAAFYKG YIPNMLGIIP YAGIDLAVYE TLKNTWLQRY AVNSADPGVF VLLACGTISS 420
TCGQLASYPL ALVRTRMQAQ ASIEGAPEVT MSSLFKQILR TEGAFGLYRG LAPNFMKVIP 480
AVSISYVVYE NLKITLGVQS R 501 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:MGI. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0055085; P:transmembrane transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |