CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023607
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PRELI domain-containing protein 1, mitochondrial 
Protein Synonyms/Alias
 25 kDa protein of relevant evolutionary and lymphoid interest; Px19-like protein 
Gene Name
 PRELID1 
Gene Synonyms/Alias
 PRELI; CGI-106; SBBI12 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
49REVTPDQKLLSRRLLubiquitination[1, 2]
160SNVTKTMKGFEYILAubiquitination[3]
168GFEYILAKLQGEAPSubiquitination[4]
176LQGEAPSKTLVETAKubiquitination[4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 May be important for the development of vital and immunocompetent organs. 
Sequence Annotation
 DOMAIN 36 174 PRELI/MSF1.  
Keyword
 Complete proteome; Mitochondrion; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 219 AA 
Protein Sequence
MVKYFLGQSV LRSSWDQVFA AFWQRYPNPY SKHVLTEDIV HREVTPDQKL LSRRLLTKTN 60
RMPRWAERLF PANVAHSVYV LEDSIVDPQN QTMTTFTWNI NHARLMVVEE RCVYCVNSDN 120
SGWTEIRREA WVSSSLFGVS RAVQEFGLAR FKSNVTKTMK GFEYILAKLQ GEAPSKTLVE 180
TAKEAKEKAK ETALAATEKA KDLASKAATK KQQQQQQFV 219 
Gene Ontology
 GO:0005739; C:mitochondrion; ISS:UniProtKB.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0006955; P:immune response; TAS:ProtInc.
 GO:0007275; P:multicellular organismal development; TAS:ProtInc. 
Interpro
 IPR006797; PRELI/MSF1. 
Pfam
 PF04707; PRELI 
SMART
  
PROSITE
 PS50904; PRELI_MSF1 
PRINTS