CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025016
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome P450, family 2, subfamily r, polypeptide 1 
Protein Synonyms/Alias
 Cytochrome P450, family 2, subfamily r, polypeptide 1, isoform CRA_a 
Gene Name
 Cyp2r1 
Gene Synonyms/Alias
 mCG_2293 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
263FLSRLIEKAAVNRKPubiquitination[1]
355RRPSWEYKCKMPYTEubiquitination[1]
434DSNGYFTKKEALIPFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 501 AA 
Protein Sequence
MLELPGARAC AGALAGALLL LLFVLVVRQL LRQRRPAGFP PGPPRLPFVG NICSLALSAD 60
LPHVYMRKQS RVYGEIFSLD LGGISTVVLN GYDVVKECLV HQSEIFADRP CLPLFMKMTK 120
MGGLLNSRYG RGWIDHRRLA VNSFHYFGSG QKSFESKILE ETWSLIDAIE TYKGGPFDLK 180
QLITNAVSNI TNLILFGERF TYEDTDFQHM IELFSENVEL AASAPVFLYN AFPWIGILPF 240
GKHQRLFRNA DVVYDFLSRL IEKAAVNRKP HLPHHFVDAY LDEMDQGQND PLSTFSKENL 300
IFSVGELIIA GTETTTNVLR WAILFMALYP NIQGQVHKEI DLIVGHNRRP SWEYKCKMPY 360
TEAVLHEVLR FCNIVPLGIF HATSEDAVVR GYSIPKGTTV ITNLYSVHFD EKYWKDPDMF 420
YPERFLDSNG YFTKKEALIP FSLGRRHCLG EQLARMEMFL FFTSLLQQFH LHFPHELVPN 480
LKPRLGMTLQ PQPYLICAER R 501 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
 GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:MGI. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.