CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037057
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 U2 snRNP-associated SURP motif-containing protein 
Protein Synonyms/Alias
  
Gene Name
 U2SURP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
168SSRFADQKNPPNQSSubiquitination[1]
391AQPRERLKNPNAPMLubiquitination[1]
409KNKEDFEKTLSQAIVubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1028 AA 
Protein Sequence
MADKTPGGSQ KASSKTRSSD VHSSGSSDAH MDASGPSDSD MPSRTRPKSP RKHNYRNESA 60
RESLCDSPHQ NLSRPLLENK LKAFSIGKMS TAKRTLSKKE QEELKKKEDE KAAAEIYEEF 120
LAAFEGSDGN KVKTFVRGGV VNAAKEEHET DEKRGKIYKP SSRFADQKNP PNQSSNERPP 180
SLLVIETKKP PLKKGEKEKK KSNLELFKEE LKQIQEERDE RHKTKGRLSR FEPPQSDSDG 240
QRRSMDAPSR RNRSSVLDDY APGSHDVGDP STTNLYLGNI NPQMNEEMLC QEFGRFGPLA 300
SVKIMWPRTD EERARERNCG FVAFMNRRDA ERALKNLNGK MIMSFEMKLG WGKAVPIPPH 360
PIYIPPSMME HTLPPPPSGL PFNAQPRERL KNPNAPMLPP PKNKEDFEKT LSQAIVKVVI 420
PTERNLLALI HRMIEFVVRE GPMFEAMIMN REINNPMFRF LFENQTPAHV YYRWKLYSIL 480
QANSPTKWRT EDFRMFKNGS FWRPPPLNPY LHGMSEEQET EAFVEEPSKK GALKEEQRDK 540
LEEILRGLTP RKNDIGDAMV FCLNNAEAAE EIVDCITESL SILKTPLPKK IARLYLVSDV 600
LYNSSAKVAN ASYYRKFFET KLCQIFSDLN ATYRTIQGHL QSENFKQRVM TCFRAWEDWA 660
IYPEPFLIKL QNIFLGLVNI IEEKETEDVP DDLDGAPIEE ELDGAPLEDV DGIPIDATPI 720
DDLDGVPIKS LDDDLDGVPL DATEDSKKNE PIFKVAPSKW EAVDESELEA QAVTTSKWEL 780
FDQHEESEEE ENQNQEEESE DEEDTQSSKS EEHHLYSNPI KEEMTESKFS KYSEMSEEKR 840
AKLREIELKV MKFQDELESG KRPKKPGQSF QEQVEHYRDK LLQREKEKEL ERERERDKKD 900
KEKLESRSKD KKEKDECTPT RKERKRRHST SPSPSRSSSG RRVKSPSPKS ERSERSERSH 960
KESSRSRSSH KDSPRDVSKK AKRSPSGSRT PKRSRRSRSR SPKKSGKKSR SQSRSPHRSH 1020
KKSKKNKH 1028 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR006569; CID_dom.
 IPR008942; ENTH_VHS.
 IPR013170; mRNA_splic_Cwf21.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR000061; Surp. 
Pfam
 PF08312; cwf21
 PF00076; RRM_1
 PF01805; Surp 
SMART
 SM00582; RPR
 SM00360; RRM
 SM00648; SWAP 
PROSITE
 PS51391; CID
 PS50102; RRM
 PS50128; SURP 
PRINTS