UniProt Accession

 HBB2_RAT; P11517 

Genbank Protein ID

 X67616; X15160; X05080; X06701; X16418; X67615; X67614 

Genbank Nucleotide ID

 CAA47876.1; CAA33250.1; CAA28738.1; CAA29887.1; CAA34440.1; CAA47875.1; CAA47874.1 

Protein Name

 Hemoglobin subunit beta-2 

Protein Synonyms/Alias

 Beta-2-globin; Hemoglobin beta chain, minor-form; Hemoglobin beta-2 chain 

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
9	VHLTDAEKATVSGLW	acetylation	[1]
18	TVSGLWGKVNADNVG	acetylation	[1]
45	WTQRYFSKFGDLSSA	acetylation	[1]
45	WTQRYFSKFGDLSSA	ubiquitination	[2]
62	IMGNPQVKAHGKKVI	acetylation	[1]
67	QVKAHGKKVINAFND	ubiquitination	[2]
77	NAFNDGLKHLDNLKG	ubiquitination	[2]
145	VASALAHKYH*****	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Involved in oxygen transport from the lung to the various peripheral tissues. 

Sequence Annotation

 METAL 64 64 Iron (heme distal ligand).
 METAL 93 93 Iron (heme proximal ligand).
 MOD_RES 36 36 Phosphotyrosine (By similarity).
 MOD_RES 42 42 Phosphotyrosine (By similarity).  

Keyword

 Complete proteome; Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport; Phosphoprotein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 147 AA 

Protein Sequence

Gene Ontology

 GO:0005833; C:hemoglobin complex; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0019825; F:oxygen binding; IEA:InterPro.
 GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. 

Interpro

 IPR000971; Globin.
 IPR009050; Globin-like.
 IPR012292; Globin_dom.
 IPR002337; Haemoglobin_b. 

Pfam

 PF00042; Globin 

SMART

  

PROSITE

 PS01033; GLOBIN 

PRINTS

 PR00814; BETAHAEM.