CPLM-023753

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-023753

UniProt Accession

PHOCN_HUMAN; Q9Y3A3; B4DML0; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y4T8

Genbank Protein ID

AB015441; AF093825; AJ580638; AF151853; AF250319; AL080070; AK027043; AK292938; AK297514; CR457371; AC020550; CH471063; CH471063; BC005237

Genbank Nucleotide ID

BAB19057.1; AAP97221.1; CAE45270.1; AAD34090.1; AAG44567.1; CAB45697.1; BAB15635.1; BAF85627.1; BAG59922.1; CAG33652.1; AAX93147.1; EAW70164.1; EAW70167.1; AAH05237.1

Protein Name

MOB-like protein phocein

Protein Synonyms/Alias

2C4D; Class II mMOB1; Mob1 homolog 3; Mob3; Mps one binder kinase activator-like 3; Preimplantation protein 3

Gene Name

MOB4

Gene Synonyms/Alias

MOB3; MOBKL3; PHOCN; PREI3; CGI-95

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
140	ACLLNSNKYFPSRVS	acetylation	[1]

Reference

[1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]

Functional Description

May play a role in membrane trafficking, specifically in membrane budding reactions (By similarity).

Sequence Annotation

METAL 92 92 Zinc (By similarity).
METAL 97 97 Zinc (By similarity).
METAL 169 169 Zinc (By similarity).
METAL 174 174 Zinc (By similarity).
MOD_RES 140 140 N6-acetyllysine.

Keyword

Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Golgi apparatus; Membrane; Metal-binding; Phosphoprotein; Reference proteome; Transport; Zinc.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

225 AA

Protein Sequence

MVMAEGTAVL RRNRPGTKAQ DFYNWPDESF DEMDSTLAVQ QYIQQNIRAD CSNIDKILEP 60
PEGQDEGVWK YEHLRQFCLE LNGLAVKLQS ECHPDTCTQM TATEQWIFLC AAHKTPKECP 120
AIDYTRHTLD GAACLLNSNK YFPSRVSIKE SSVAKLGSVC RRIYRIFSHA YFHHRQIFDE 180
YENETFLCHR FTKFVMKYNL MSKDNLIVPI LEEEVQNSVS GESEA 225

Gene Ontology

GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.

Interpro

IPR005301; Mob1_phocein.

Pfam

PF03637; Mob1_phocein

SMART

PROSITE

PRINTS