CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041258
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 OTU domain containing 4, isoform CRA_f 
Protein Synonyms/Alias
 OTU domain-containing protein 4 
Gene Name
 OTUD4 
Gene Synonyms/Alias
 hCG_2026279 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
41LYRKLVAKDGSCLFRacetylation[1]
1040ILRSGRSKQFYNQTYubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1114 AA 
Protein Sequence
MEAAVGVPDG GDQGGAGPRE DATPMDAYLR KLGLYRKLVA KDGSCLFRAV AEQVLHSQSR 60
HVEVRMACIH YLRENREKFE AFIEGSFEEY LKRLENPQEW VGQVEISALS LMYRKDFIIY 120
REPNVSPSQV TENNFPEKVL LCFSNGNHYD IVYPIKYKES SAMCQSLLYE LLYEKVFKTD 180
VSKIVMELDT LEVADEDNSE ISDSEDDSCK SKTAAAAADV NGFKPLSGNE QLKNNGNSTS 240
LPLSRKVLKS LNPAVYRNVE YEIWLKSKQA QQKRDYSIAA GLQYEVGDKC QVRLDHNGKF 300
LNADVQGIHS ENGPVLVEEL GKKHTSKNLK APPPESWNTV SGKKMKKPST SGQNFHSDVD 360
YRGPKNPSKP IKAPSALPPR LQHPSGVRQH AFSSHSSGSQ SQKFSSEHKN LSRTPSQIIR 420
KPDRERVEDF DHTSRESNYF GLSPEERREK QAIEESRLLY EIQNRDEQAF PALSSSSVNQ 480
SASQSSNPCV QRKSSHVGDR KGSRRRMDTE ERKDKDSIHG HSQLDKRPEP STLENITDDK 540
YATVSSPSKS KKLECPSPAE QKPAEHVSLS NPAPLLVSPE VHLTPAVPSL PATVPAWPSE 600
PTTFGPTGVP APIPVLSVTQ TLTTGPDSAV SQAHLTPSPV PVSIQAVNQP LMPLPQTLSL 660
YQDPLYPGFP CNEKGDRAIV PPYSLCQTGE DLPKDKNILR FFFNLGVKAY SCPMWAPHSY 720
LYPLHQAYLA ACRMYPKVPV PVYPHNPWFQ EAPAAQNESD CTCTDAHFPM QTEASVNGQM 780
PQPEIGPPTF SSPLVIPPSQ VSESHGQLSY QADLESETPG QLLHADYEES LSGKNMFPQP 840
SFGPNPFLGP VPIAPPFFPH VWYGYPFQGF IENPVMRQNI VLPSDEKGEL DLSLENLDLS 900
KDCGSVSTVD EFPEARGEHV HSLPEASVSS KPDEGRTEQS SQTRKADTAL ASIPPVAEGK 960
AHPPTQILNR ERETVPVELE PKRTIQSLKE KTEKVKDPKT AADVVSPGAN SVDSRVQRPK 1020
EESSEDENEV SNILRSGRSK QFYNQTYGSR KYKSDWGYSG RGGYQHVRSE ESWKGQPSRS 1080
RDEGYQYHRN VRGRPFRGDR RRSGMGDGHR GQHT 1114 
Gene Ontology
  
Interpro
 IPR003323; OTU. 
Pfam
 PF02338; OTU 
SMART
  
PROSITE
 PS50802; OTU 
PRINTS