CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045626
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 
Protein Synonyms/Alias
  
Gene Name
 Atp2a1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
30GLTPDQVKRHLEKYGacetylation[1]
35QVKRHLEKYGPNELPacetylation[1]
158VEVAVGDKVPADIRIacetylation[1]
246MAATEQDKTPLQQKLacetylation[1]
464TEVRSLSKVERANACacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 989 AA 
Protein Sequence
MEAAHSKSTE ECLSYFGVSE TTGLTPDQVK RHLEKYGPNE LPAEEGKSLW ELVVEQFEDL 60
LVRILLLAAC ISFVLAWFEE GEETVTAFVE PFVILLILIA NAIVGVWQER NAENAIEALK 120
EYEPEMGKVY RADRKSVQRI KARDIVPGDI VEVAVGDKVP ADIRILSIKS TTLRVDQSIL 180
TGESVSVIKH TDPVPDPRAV NQDKKNMLFS GTNIAAGKAV GIVATTGVST EIGKIRDQMA 240
ATEQDKTPLQ QKLDEFGEQL SKVISLICVA VWLINIGHFN DPVHGGSWFR GAIYYFKIAV 300
ALAVAAIPEG LPAVITTCLA LGTRRMAKKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ 360
MSVCKMFIID KVDGDICSLN EFSITGSTYA PEGEVLKNDK PVRAGQYDGL VELATICALC 420
NDSSLDFNET KGVYEKVGEA TETALTTLVE KMNVFNTEVR SLSKVERANA CNSVRPQWLY 480
PLLFQSRLSS VKIPFPHINI AMLGSKVCSV FLTEQALALP VYAGIIRNEK FPGPLLPRSC 540
CFPKTRSQGS RPQLHQHYCP SSSELPPVCP KFLPDLSPSL SFQMDLTFVG VVGMLDPPRK 600
EVTGSIQLCR DAGIRVIMIT GDNKGTAIAI CRRIGIFSEN EEVADRAYTG REFDDLPLAE 660
QREACRRACC FARVEPSHKS KIVEYLQSYD EITAMTGDGV NDAPALKKAE IGIAMGSGTA 720
VAKTASEMVL ADDNFSTIVA AVEEGRAIYN NMKQFIRYLI SSNVGEVVCI FLTAALGLPE 780
ALIPVQLLWV NLVTDGLPAT ALGFNPPDLD IMDRPPRSPK EPLISGWLFF RYMAIGGYVG 840
AATVGAAAWW FLYAEDGPHV SYHQLTHFMQ CTEHNPEFDG LDCEVFEAPE PMTMALSVLV 900
TIEMCNALNS LSENQSLLRM PPWVNIWLLG SICLSMSLHF LILYVDPLPM IFKLRALDFT 960
QWLMVLKISL PVIGLDELLK FIARNYLEG 989 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR004014; ATPase_P-typ_cation-transptr_N.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00690; Cation_ATPase_N
 PF00122; E1-E2_ATPase
 PF00702; Hydrolase 
SMART
 SM00831; Cation_ATPase_N 
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.
 PR00120; HATPASE.