CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011384
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SKG3 
Protein Synonyms/Alias
 Suppressor of lethality of KEX2-GAS1 double null mutant protein 3 
Gene Name
 SKG3 
Gene Synonyms/Alias
 YLR187W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
21SAPPKVFKNDESPSTubiquitination[1]
638NSSPKPQKLEVKDRSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 May play a role in cell wall integrity. 
Sequence Annotation
 DOMAIN 90 221 PH 1.
 DOMAIN 254 433 PH 2.
 MOD_RES 10 10 Phosphoserine.
 MOD_RES 31 31 Phosphoserine.
 MOD_RES 578 578 Phosphothreonine.
 MOD_RES 580 580 Phosphoserine.
 MOD_RES 592 592 Phosphoserine.
 MOD_RES 701 701 Phosphoserine.
 MOD_RES 954 954 Phosphoserine.  
Keyword
 Cell membrane; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1026 AA 
Protein Sequence
MKRIFSGVKS PKLSAPPKVF KNDESPSTPS SPKFDQGLRS LSASASRLFS NSISTPGSPT 60
LDLPQEHSIN GDISPELVPI VTLLSAQAHR RYHYGIFLIL HDLKTDGTPA ARQWEECYGV 120
LLGTQLALWD AKELSDSKNN KNTSTMKKAA SRPSFINFTD ASVRSLDAND QVIIASENEK 180
TKKDLDNVLV VSTTLKNRYF LKFKNSKSFK TWNAAIRLSL FEFTALQEAY TGSFLSSRGV 240
KLGDIKVVMA DTKFTYEDWV SVRFGTGMPW KRCYAVISPQ SGKKKKNSKG SICFYENNKK 300
TKKSNIMTTV VDARALYAVY PSSPILIDTS TIIKLEGFVS FDKSEEPQET NLFIMPEKHQ 360
GVPGYDTIIR FLIPAMNAFY LYGRPKGLIA NRTDPDSLLF ALPTLPHIYY LQVDDVLSLT 420
KDKNYIHWSA ADWRNNIVQV LQKKLSKGYK GCGNKTVSVS SGMMKSPAIS SAELFEGYDS 480
LPERQMESPQ KSKMKSPTLA STDDINSASA SVNSHATSVK QTELFVTDNS SKINDSVSAQ 540
SSVTTNFKDT FTTPMTSGML NHENSERSFG SGLKLKITDS NLENMEDVEA KSANEFSTTP 600
EDKHIHLANA AELSALYDKY STSPFGKSEA NSSPKPQKLE VKDRSKNENR SPYERYVGTS 660
AESKTFEIGN VRESKSTINT SLSSPLRVED SRRSKNEDLG SLKEFEELSQ KISNMGMANI 720
SSEALSDTAE NSSFVTDLNL NINNSSSVNL NEEQRVPDFG EENVFDPDYM EQNQMLETES 780
RYTTDEFDFS DNQDAASSNY SNGQTNRTVT ETLSASDRND KIPHSSLFTN LNQLTSNGGN 840
YQDREDFSGD QINKPQQSQP LHVKGPQTSS FGYRNSSANS SQPQAPYPVG RPLGKIRTGP 900
LTVQPMQQGG NSSMYSFQSS QHRFHSSQQR QNQSLSFRNN TYGSGNNQNT FHPSPQLQQQ 960
PQNMRYLNNK LPINDRSPIP QTQHHVPDGR PSLHINTTNR TNPLTAQSGF SQFMPPNSTS 1020
TNPYSS 1026 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS