CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041784
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 E74-like factor 1, isoform CRA_b 
Protein Synonyms/Alias
 Protein Elf1 
Gene Name
 Elf1 
Gene Synonyms/Alias
 rCG_37183 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
337MSSSPGIKGGATTILacetylation[1]
345GGATTILKPGNPKVAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 615 AA 
Protein Sequence
MAAVVQQNDL VFDFASNVME DEQQLGDPAI FPAVIVEHVP GADILNGYAG LACVEEPNDM 60
ITESSLDVAE EEIIEDDDDD ITLTVEASCH NGDETIETIG AAEALLNMDS PGPVLDEKRI 120
NNNIFSSSED DIVAPITHVS VTLDGIPEVM ETQQVQESNA DSPGASSPEQ PKRKKGRKTK 180
PPRPDSPATT PNISVKKKSK DGKGNTIYLW EFLLALLQDK ATCPKYIKWT QREKGIFKLV 240
DSKAVSRLWG KHKNKPDMNY ETMGRALRYY YQRGILAKVE GQRLVYQFKE MPKDLIYIDD 300
EGPSSSTESS DQSLSSTTTS SRNQANRTRM SSSPGIKGGA TTILKPGNPK VAKPKDTVEV 360
GQPSEVLRTV QPSQAPYPTQ LFRTVHVVQP VQAIPEEATI TSTMQEEAAG SSVQGIRTIQ 420
ASTQVPVVVS PGNQQLHTVT LQTVPLTTVI ASTDPSSGAG PQKFILQAIP SSQPMTVLKE 480
NVLLQSQKPG SPPSIVFSPT PVQQVLTGSV QSLGNGAVSM ASPPNFSATA PVVTFSRSSQ 540
LAAHPPGTVI TSVIKAQETK TPKAEVEKKA EGHLNGDPEE IEQQPQPYVM VVSSSNGFSS 600
QVAITQNELL EPSSF 615 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0050860; P:negative regulation of T cell receptor signaling pathway; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0001817; P:regulation of cytokine production; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IMP:RGD. 
Interpro
 IPR000418; Ets_dom.
 IPR022084; TF_Elf_N.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF12310; Elf-1_N
 PF00178; Ets 
SMART
 SM00413; ETS 
PROSITE
 PS00345; ETS_DOMAIN_1
 PS00346; ETS_DOMAIN_2
 PS50061; ETS_DOMAIN_3 
PRINTS
 PR00454; ETSDOMAIN.