CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010372
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Elongation factor Ts 
Protein Synonyms/Alias
 EF-Ts 
Gene Name
 tsf 
Gene Synonyms/Alias
 MPN_631; MP211 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
4****MATKIELIKELacetylation[1]
35QNNDDLEKAIKWLREacetylation[1]
38DDLEKAIKWLRENGIacetylation[1]
101LMISEVFKKATPTTTacetylation[1]
120TQYELQGKEKVAERLacetylation[1]
133RLALVASKTDEKIVLacetylation[1]
137VASKTDEKIVLRRLMacetylation[1]
215SIIKSQAKLEVQDNPacetylation[1]
230KKAAFLDKTIAGRVNacetylation[1]
263KTVGQFLKEKNSKVIacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity). 
Sequence Annotation
 REGION 79 82 Involved in Mg(2+) ion dislocation from  
Keyword
 Complete proteome; Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
MATKIELIKE LRKTTQASMM DCKKALEQNN DDLEKAIKWL RENGIVKSAK KLGKVAADGC 60
IVLHSDHHKA VMVEINSQTD FVARSQELTD FAQLMISEVF KKATPTTTIE EVTQYELQGK 120
EKVAERLALV ASKTDEKIVL RRLMVFESKT NHIFSYLHAN KRIGVILEVE GKFDEQDGKH 180
LAMHIAANSP QFIDQDNVDQ TWLANETSII KSQAKLEVQD NPKKAAFLDK TIAGRVNKLL 240
IDICLVNQKY LVDESKTVGQ FLKEKNSKVI HFVRFEVGEG IVKEAVDFAS EVSAQMKK 298 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003746; F:translation elongation factor activity; IEA:HAMAP. 
Interpro
 IPR001816; Transl_elong_EFTs/EF1B.
 IPR014039; Transl_elong_EFTs/EF1B_dimer.
 IPR018101; Transl_elong_Ts_CS.
 IPR009060; UBA-like.
 IPR000449; UBA/transl_elong_EF1B_N. 
Pfam
 PF00889; EF_TS
 PF00627; UBA 
SMART
  
PROSITE
 PS01126; EF_TS_1
 PS01127; EF_TS_2 
PRINTS