UniProt Accession

 CSK2B_RAT; P67874; P07312; P13862 

Genbank Protein ID

 L15619; BX883045 

Genbank Nucleotide ID

 AAA40928.1; CAE83994.1 

Protein Name

 Casein kinase II subunit beta 

Protein Synonyms/Alias

 CK II beta; Phosvitin 

Gene Name

 Csnk2b 

Gene Synonyms/Alias

 Ck2n 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
212	SNFKSPVKTIR****	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). 

Sequence Annotation

 REGION 188 193 Interaction with alpha subunit.
 METAL 109 109 Zinc.
 METAL 114 114 Zinc.
 METAL 137 137 Zinc.
 METAL 140 140 Zinc.
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 2 2 Phosphoserine; by autocatalysis
 MOD_RES 3 3 Phosphoserine; by autocatalysis (By
 MOD_RES 209 209 Phosphoserine (By similarity).
 MOD_RES 212 212 N6-acetyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Wnt signaling pathway; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 215 AA 

Protein Sequence

Gene Ontology

 GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
 GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:RGD.
 GO:0030177; P:positive regulation of Wnt receptor signaling pathway; TAS:RGD.
 GO:0045859; P:regulation of protein kinase activity; IEA:GOC.
 GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. 

Interpro

 IPR016149; Casein_kin_II_reg-sub_a-hlx.
 IPR016150; Casein_kin_II_reg-sub_b-sht.
 IPR000704; Casein_kinase_II_reg-sub. 

Pfam

 PF01214; CK_II_beta 

SMART

 SM01085; CK_II_beta 

PROSITE

 PS01101; CK2_BETA 

PRINTS

 PR00472; CASNKINASEII.