CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041530
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein LOC100360745 
Protein Synonyms/Alias
 RCG20940 
Gene Name
 LOC100360745 
Gene Synonyms/Alias
 rCG_20940 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
261AKNTWTLKKLPLSLSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; G-protein coupled receptor; Membrane; Receptor; Reference proteome; Transducer; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 764 AA 
Protein Sequence
MRPGSLLQLT LLLALPRSLW GRGCTSPPCE CHQEDDFRVT CKELHRIPSL PPSTQTLKLI 60
ETHLKTIPSL AFSSLPNISR IYLSIDATLQ RLEPHSFYNL SKMTHIEIRN TRSLTYIDPD 120
ALTELPLLKF LGIFNTGLRI FPDLTKIYST DVFFILEITD NPYMTSVPEN AFQGLCNETL 180
TLKLYNNGFT SIQGHAFNGT KLDAVYLNKN KYLTAIDKDA FGGVYSGPTL LDVSSTSVTA 240
LPSKGLEHLK ELIAKNTWTL KKLPLSLSFL HLTRADLSYP SHCCAFKNQK KIRGILESLM 300
CNESSIRNLR QRKSVNVMRG PVYQEYEEGL GDNHVGYKQN SKFQEGPSNS HYYVFFEEQE 360
DEIIGFGQEL KNPQEETLQA FDSHYDYTVC GDNEDMVCTP KSDEFNPCED IMGYKFLRIV 420
VWFVSLMALL GNVFVLFVLL TSHYKLTVPR FLMCNLAFAD FCMGVYLLLI ASVDLYTHTE 480
YYNHAIDWQT GPGCNTAGFF TVFASELSVY TLTVITLERW YAITFAMRLD RKIRLRHAYT 540
IMAGGWVSCF LLALLPMVGI SSYAKVSICL PMDTDTPLAL AYIALVLLLN VVAFVIVCSC 600
YVKIYITVRN PQYNPRDKDT KIAKRMAVLI FTDFMCMAPI SFYALSALMN KPLITVTNSK 660
ILLVLFYPLN SCANPFLYAI FTKAFQRDVF ILLSKFGLCK HQAQAYQAQR VCPNNNTGIQ 720
IQKIPQDTRQ SLPNVQDTYE PLGSSHLTPK LQGRISEEYT QTAL 764 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004996; F:thyroid-stimulating hormone receptor activity; IEA:Compara.
 GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Compara.
 GO:0008344; P:adult locomotory behavior; IEA:Compara.
 GO:0030183; P:B cell differentiation; IEA:Compara.
 GO:0040018; P:positive regulation of multicellular organism growth; IEA:Compara.
 GO:0040012; P:regulation of locomotion; IEA:Compara. 
Interpro
 IPR000276; GPCR_Rhodpsn.
 IPR017452; GPCR_Rhodpsn_7TM.
 IPR002131; Gphrmn_rcpt.
 IPR026906; LRR_5.
 IPR002274; TSH_rcpt. 
Pfam
 PF00001; 7tm_1
 PF13306; LRR_5 
SMART
  
PROSITE
 PS00237; G_PROTEIN_RECEP_F1_1
 PS50262; G_PROTEIN_RECEP_F1_2 
PRINTS
 PR00373; GLYCHORMONER.
 PR00237; GPCRRHODOPSN.
 PR01145; TSHRECEPTOR.