CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029518
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AN1-type zinc finger protein 2A 
Protein Synonyms/Alias
 Zinc finger, AN1-type domain 2A, isoform CRA_b 
Gene Name
 ZFAND2A 
Gene Synonyms/Alias
 hCG_1744855 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34ACKQDFCKDHFPYAAubiquitination[1, 2, 3]
50KCPFAFQKDVHVPVCubiquitination[2]
67CNTPIPVKKGQIPDVubiquitination[1, 4]
68NTPIPVKKGQIPDVVubiquitination[2]
90DCDSHPGKKKEKSLCubiquitination[1]
91CDSHPGKKKEKSLCSubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 205 AA 
Protein Sequence
MEFPDLGKHC SEKTCKQLDF LPVKCDACKQ DFCKDHFPYA AHKCPFAFQK DVHVPVCPLC 60
NTPIPVKKGQ IPDVVVGDHI DRDCDSHPGK KKEKSLCSLR FLHTVAQKRA ARRKRCCRWY 120
VPNVTATSVS STDTLWTTAA DTGVAPPSKL GEKRLRCDGS EHAVACVEAA YTLVGSGAPL 180
STIPHWLLIL FVEGDGTIIK LNAEV 205 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR000058; Znf_AN1. 
Pfam
 PF01428; zf-AN1 
SMART
  
PROSITE
  
PRINTS