CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032478
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GARNL1 protein 
Protein Synonyms/Alias
 Ral GTPase-activating protein subunit alpha-1 
Gene Name
 GARNL1 
Gene Synonyms/Alias
 RALGAPA1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1910SDDSLTKKLRHLGNDubiquitination[1]
1997INASRALKSLIPLYQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2049 AA 
Protein Sequence
MFSKKPHGDV KKSTQKVLDT KKDALTRLKH LRIVIENAES IDLKQFFDQH FSHIYYVFFE 60
NFVTIEASLK QKGHKSQREE LDAILFIFEK ILQLLPERIH QRWQFHSIGL ILKKLLHTGN 120
SLKIRREGVR LFLLWLQALQ NNCSKEQLWM FSCLIPGFSA PQSEHGPRTL DNLINPPLNL 180
QETQVTIEEI TPLVPPQSGD KGQEDLTSYF LEALLKYIVI QVKSLEWKNK ENQERGFSFL 240
FSHFKKYYLP YIFPNICKEN SLYHPILDIP QMRPKPHYVV IKKDAETNEA IYCTKEPFIK 300
ARVIVIRWLV SFWLEPKPHT GPHIPGMEGE VLPKNIQRAA ASLVSREESK NDNADKTDRT 360
TEPEQSHSNT STLTEREPSS SSLCSIDEEH LTDIEIVRRV FSSKRSNVNF VTEIFRQAFL 420
LPICEAAAMR KVVKVYQEWI QQEEKPLFMQ EPEEIVITSS DLPCIENVTD HDISMEEGEK 480
REEENGTNTA DHVRNSSWAK NGSYQGALHN ASEEATEQNI RAGTQAVLQV FIINSSNIFL 540
LEPANEIKNL LDEHTDMCKR ILNIYRYMVV QVSMDKKTWE QMLLVLLRVT ESVLKMPSQA 600
FLQFQGKKNM TLAGRLAGPL FQTLIVAWIK ANLNVYISRE LWDDLLSVLS SLTYWEELAT 660
EWSLTMETLT KVLARNLYSL DLSDLPLDKL SEQKQKKHKG KGVGHEFQKV SVDKSFSRGW 720
SRDQPGQAPM RQRSATTTGS PGTEKARSIV RQKTVDIDDA QILPRSTRVR HFSQSEETGN 780
EVFGALNEEQ PLPRSSSTSD ILEPFTVERA KEAEQNATRG STEGSVQSCN GLFWKESCSD 840
IGGSSANVPD LMDEFIAERL RSGNASTMTR RGSSPGSLEI PKDLPDILNK QNQMRPIDDP 900
GVPSEWTSPA SAGSSDLISS DSHSDSFSAF QYDGRKFDNF GFGTDTGVTS SADVDSGSGH 960
HQSAEEQEVA SLTTLHIDSE TSSLNQQAFS AEVATITGSE SASPVHSPLG SRSQTPSPST 1020
LNIDHMEQKD LQLDEKLHHS VLQTPDDLEI SEFPSECCSV MAGGTLTGWH ADVATVMWRR 1080
MLGILGDVNS IMDPEIHAQV FDYLCELWQN LAKIRDNLGI STDNLTSPSP PVLIPPLRIL 1140
TPWLFKATML TDKYKQGKLH AYKLICNTMK RRQDVSPNRD FLTHFYNIMH CGLLHIDQDI 1200
VNTIIKHCSP QFFSLGLPGA TMLIMDFIVA AGRVASSAFL NAPRVEAQVL LGSLVCFPNL 1260
YCELPSLHPN IPDVAVSQFT DVKELIIKTV LSSARDEPSG PARCVALCSL GIWICEELVH 1320
ESHHPQIKEA LNVICVSLKF TNKTVAHVAC NMLHMLVHYV PRLQIYQPDS PLKIIQILIA 1380
TITHLLPSTE ASSYEMDKRL VVSLLLCLLD WIMALPLKTL LQPFHATGAE SDKTEKSVLN 1440
CIYKVLHGCV YGAQCFSNPR YFPMSLSDLA SVDYDPFMHL ESLKEPEPLH SPDSERSSKL 1500
QPVTEVKTQM QHGLISIAAR TVITHLVNHL GHYPMSGGPA MLTSQVCENH DNHYSESTEL 1560
SPELFESPNI QFFVLNNTTL VSCIQIRSEE NMPGGGLSAG LASANSNVRI IVRDLSGKYS 1620
WDSAILYGPP PVSGLSEPTS FMLSLSHQEK PEEPPTSNEC LEDITVKDGL SLQFKRFRET 1680
VPTWDTIRDE EDVLDELLQY LGVTSPECLQ RTGISLNIPA PQPVCISEKQ ENDVINAILK 1740
QHTEEKEFVE KHFNDLNMKA VEQDEPIPQK PQSAFYYCRL LLSILGMNSW DKRRSFHLLK 1800
KNEKLLRELR NLDSRQCRET HKIAVFYVAE GQEDKHSILT NTGGSQAYED FVAGLGWEVN 1860
LTNHCGFMGG LQKNKSTGLT TPYFATSTVE VIFHVSTRMP SDSDDSLTKK LRHLGNDEVH 1920
IVWSEHTRDY RRGIIPTEFG DVLIVIYPMK NHMFSIQIMK KPEVPFFGPL FDGAIVNGKV 1980
LPIMVRATAI NASRALKSLI PLYQNFYEER ARYLQTIVQH HLEPTTFEDF AAQVFSPAPY 2040
HHLPSDADH 2049 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR000331; Rap_GAP_dom.
 IPR027107; Tuberin/Ral-act_asu. 
Pfam
 PF02145; Rap_GAP 
SMART
  
PROSITE
 PS50085; RAPGAP 
PRINTS