CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037275
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Bardet-Biedl syndrome 5 protein 
Protein Synonyms/Alias
 Uncharacterized protein 
Gene Name
 BBS5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
135HRAYETSKMYRDFKLubiquitination[1]
150RSALIQNKQLRLLPQubiquitination[1]
248EKLQESVKEINSLHKubiquitination[1]
521KEWAGMLKEIRYASGubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 544 AA 
Protein Sequence
MSVLDALWED RDVRFDLSAQ QMKTRPGEVL IDCLDSIEDT KGNNGDRGRL LVTNLRILWH 60
SLALSRVNVS VGYNCILNIT TRTANSKLRG QTEALYILTK CNSTRFEFIF TNLVPGSPRL 120
FTSVMAVHRA YETSKMYRDF KLRSALIQNK QLRLLPQEHV YDKINGVWNL SSDQGNLGTF 180
FITNVRIVWH ANMNDSFNVS IPYLQIRSIK IRDSKFGLAL VIESSQQSGG YVLGFKIDPV 240
EKLQESVKEI NSLHKVYSAS PIFGVDYEME EKPQPLEALT VEQIQDDVEI DSDGHTDAFV 300
AYFADGNKLD SIASEWVGLP PLPSARCLFG LGEVDDKIYV VAGKDLQTEA SLDSVLCYDP 360
VAAKWNEVKK LPIKVYGHNV ISHKGMIYCL GGKTDDKKCT NRVFIFNPKK GDWKDLAPMK 420
IPRSMFGVAV HKGKIVIAGG VTEDGLSASV EAFDLTTNKW DVMTEFPQER SSISLVSLAG 480
SLYAIGGFAM IQLESKEFAP TEVNDIWKYE DDKKEWAGML KEIRYASGAS CLATRLNLFK 540
LSKL 544 
Gene Ontology
  
Interpro
 IPR006606; BBL5.
 IPR015915; Kelch-typ_b-propeller.
 IPR006652; Kelch_1. 
Pfam
 PF07289; DUF1448
 PF01344; Kelch_1 
SMART
 SM00612; Kelch 
PROSITE
  
PRINTS