UniProt Accession

 E9PZH6_MOUSE; E9PZH6 

Genbank Protein ID

 AC130718; AC147624 

Genbank Nucleotide ID

  

Protein Name

 WW domain-containing adapter protein with coiled-coil 

Protein Synonyms/Alias

  

Gene Name

 Wac 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
257	TASLPAQKTERKESA	acetylation	[1, 2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 339 AA 

Protein Sequence

Gene Ontology

 GO:0005681; C:spliceosomal complex; IDA:MGI.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0000075; P:cell cycle checkpoint; IEA:Compara.
 GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IEA:Compara.
 GO:0010390; P:histone monoubiquitination; IEA:Compara.
 GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Compara.
 GO:0016239; P:positive regulation of macroautophagy; IEA:Compara.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0006974; P:response to DNA damage stimulus; IEA:Compara. 

Interpro

 IPR001202; WW_dom. 

Pfam

 PF00397; WW 

SMART

 SM00456; WW 

PROSITE

 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 

PRINTS