| Tag | Content |
|---|
| CPLM ID | CPLM-006604 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-dependent RNA helicase DBP7 |
Protein Synonyms/Alias | DEAD box protein 7 |
Gene Name | DBP7 |
Gene Synonyms/Alias | YKR024C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 734 | RMARMAEKQIASEFN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. |
Sequence Annotation | DOMAIN 178 372 Helicase ATP-binding.
DOMAIN 405 605 Helicase C-terminal.
NP_BIND 191 198 ATP (By similarity).
MOTIF 143 172 Q motif.
MOTIF 307 310 DEGD box. |
Keyword | ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 742 AA |
Protein Sequence | MSDEDSMLLN FTTNEDTAGS SYKQAAKVTG GRWKDRRRMK MKLEGKTVSR KRKANTTGDE 60
GIIPGRGENS IKKLHKESSY SSEEQEKYKG RNAHNTQGRT LPADSQFVSS LFTSNREITT 120
AVNTNIHDEN VAINPSNAPL KGDQFASLGV SSLLVSHLEQ KMRIKKPTSI QKQAIPQIIG 180
NAGKNDFFIH AQTGSGKTLS YLLPIISTIL NMDTHVDRTS GAFALVIAPT RELASQIYHV 240
CSTLVSCCHY LVPCLLIGGE RKKSEKARLR KGCNFIIGTP GRVLDHLQNT KVIKEQLSQS 300
LRYIVLDEGD KLMELGFDET ISEIIKIVHD IPINSEKFPK LPHKLVHMLC SATLTDGVNR 360
LRNVALKDYK LISNGTKKDS DIVTVAPDQL LQRITIVPPK LRLVTLAATL NNITKDFIAS 420
GQQSKTLRTI VFVSCSDSVE FHYDAFSGSD GHHKNLTGDS VRLLTKGNTM FPCFSDSRDP 480
DVVIYKLHGS LSQQMRTSTL QHFARDNEAT KGKHLIMFCT DVASRGLDLP HVGSVIELDP 540
PFAVEDHLHR VGRTARAGEK GESLLFLLPG EEEKYMDYIQ PYHPMGWELL KFDKEILMPA 600
FKDVNVNRND KFIRKDEKSS KNKDVGDKEY EWDTNATTWH LNIERRVVGD SAFKNLAVKG 660
FISHVRAYAT HISQEKKFFN VKFLHLGHLA KSFGLRERPK AMGLQSSKDG NSEKKPTKEN 720
SKNKMFRMAR MAEKQIASEF NY 742 |
Gene Ontology | GO:0005730; C:nucleolus; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004004; F:ATP-dependent RNA helicase activity; ISS:SGD. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. |
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SMART | |
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