CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002131
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Calcium vector protein 
Protein Synonyms/Alias
 CAVP 
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Branchiostoma lanceolatum (Common lancelet) (Amphioxus) 
NCBI Taxa ID
 7740 
Lysine Modification
Position
Peptide
Type
References
96EEILRAFKVFDANGDmethylation[1]
117EFKFIMQKVGEEPLTmethylation[1]
Reference
 [1] Update on activities at the Universal Protein Resource (UniProt) in 2013.
 e="String">UniProt Consortium.
 Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [PMID: 23161681
Functional Description
 The exact function of this protein is not yet known. It interacts with CAVPT, a protein also of unknown function, in a calcium-dependent way. This protein binds two calcium ions. 
Sequence Annotation
 DOMAIN 12 47 EF-hand 1.
 DOMAIN 49 84 EF-hand 2.
 DOMAIN 86 121 EF-hand 3.
 DOMAIN 123 158 EF-hand 4.
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 96 96 N6,N6,N6-trimethyllysine.
 MOD_RES 117 117 N6,N6,N6-trimethyllysine.  
Keyword
 3D-structure; Acetylation; Calcium; Cytoplasm; Direct protein sequencing; Metal-binding; Methylation; Muscle protein; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 162 AA 
Protein Sequence
MAAPKARALG PEEKDECMKI FDIFDRNAEN IAPVSDTMDM LTKLGQTYTK RETEAIMKEA 60
RGPKGDKKNI GPEEWLTLCS KWVRQDDEEE ILRAFKVFDA NGDGVIDFDE FKFIMQKVGE 120
EPLTDAEVEE AMKEADEDGN GVIDIPEFMD LIKKSKNALK ES 162 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001125; Recoverin. 
Pfam
 PF00036; efhand 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS
 PR00450; RECOVERIN.