UniProt Accession

 DRS7B_MOUSE; Q99J47; Q3UNS3; Q5NCT5 

Genbank Protein ID

 AK052209; AK139084; AK144057; AL596215; BC003479 

Genbank Nucleotide ID

 BAC34887.1; BAE23884.1; BAE25674.1; CAI35261.1; AAH03479.1 

Protein Name

 Dehydrogenase/reductase SDR family member 7B 

Protein Synonyms/Alias

  

Gene Name

 Dhrs7b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
87	VLCGRNVKALEELSR	ubiquitination	[1]
159	TIVDVDRKVMEINYF	ubiquitination	[1]
209	RSAYSASKHATQAFF	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Putative oxidoreductase (Potential). 

Sequence Annotation

 NP_BIND 56 80 NAD or NADP (By similarity).
 ACT_SITE 205 205 Proton acceptor (By similarity).
 BINDING 192 192 Substrate (Potential).  

Keyword

 Alternative splicing; Complete proteome; Membrane; NAD; NADP; Oxidoreductase; Peroxisome; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 323 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 

Interpro

 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 

Pfam

 PF00106; adh_short 

SMART

  

PROSITE

 PS00061; ADH_SHORT 

PRINTS

 PR00081; GDHRDH.
 PR00080; SDRFAMILY.