CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007966
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cysteine and glycine-rich protein 1 
Protein Synonyms/Alias
 Cysteine-rich protein 1; CRP; CRP1 
Gene Name
 Csrp1 
Gene Synonyms/Alias
 Csrp 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
8MPNWGGGKKCGVCQKacetylation[1]
84AGTLSMDKGESLGIKacetylation[1]
91KGESLGIKHEEAPGHacetylation[1]
108TTNPNASKFAQKIGGacetylation[1]
112NASKFAQKIGGSERCacetylation[1]
131QAVYAAEKVIGAGKSacetylation[1]
137EKVIGAGKSWHKSCFacetylation[1]
141GAGKSWHKSCFRCAKacetylation[1]
161ESTTLADKDGEIYCKacetylation[1]
178YAKNFGPKGFGFGQGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Could play a role in neuronal development. 
Sequence Annotation
 DOMAIN 10 61 LIM zinc-binding 1.
 DOMAIN 119 170 LIM zinc-binding 2.
 MOTIF 64 69 Nuclear localization signal (Potential).
 MOD_RES 112 112 N6-acetyllysine (By similarity).
 MOD_RES 127 127 Phosphotyrosine (By similarity).
 MOD_RES 131 131 N6-acetyllysine (By similarity).
 MOD_RES 192 192 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; LIM domain; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 193 AA 
Protein Sequence
MPNWGGGKKC GVCQKTVYFA EEVQCEGNSF HKSCFLCMVC KKNLDSTTVA VHGEEIYCKS 60
CYGKKYGPKG YGYGQGAGTL SMDKGESLGI KHEEAPGHRP TTNPNASKFA QKIGGSERCP 120
RCSQAVYAAE KVIGAGKSWH KSCFRCAKCG KGLESTTLAD KDGEIYCKGC YAKNFGPKGF 180
GFGQGAGALV HSE 193 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007399; P:nervous system development; NAS:RGD. 
Interpro
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM 
SMART
 SM00132; LIM 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 
PRINTS