CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009165
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Palmitoyltransferase ZDHHC9 
Protein Synonyms/Alias
 Zinc finger DHHC domain-containing protein 9; DHHC-9; DHHC9 
Gene Name
 Zdhhc9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
127QRPPPRIKNFQINNQubiquitination[1]
137QINNQIVKLKYCYTCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (By similarity). 
Sequence Annotation
 ZN_FING 139 189 DHHC-type.
 ACT_SITE 169 169 S-palmitoyl cysteine intermediate (By  
Keyword
 Acyltransferase; Complete proteome; Endoplasmic reticulum; Golgi apparatus; Membrane; Metal-binding; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 364 AA 
Protein Sequence
MSVMVVRKKV TRKWEKLPGR NTFCCDGRVM MARQKGIFYL TLFLILGTCT LFFAFECRYL 60
AVQLSPAIPV FAAMLFLFSM ATLLRTSFSD PGVIPRALPD EAAFIEMEIE ATNGAVPQGQ 120
RPPPRIKNFQ INNQIVKLKY CYTCKIFRPP RASHCSICDN CVERFDHHCP WVGNCVGKRN 180
YRYFYLFILS LSLLTIYVFA FNIVYVALKS LKIGFLETLK ETPGTVLEVL ICFFTLWSVV 240
GLTGFHTFLV ALNQTTNEDI KGSWTGKNRV QNPYSHGNIV KNCCEVLCGP LPPSVLDRRG 300
ILPLEESGSR PPSTQETSSS LLPQSPASTE HMNSNEMAED TSIPEEMPPP EPPEPPQEAS 360
EAEK 364 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001594; Znf_DHHC_palmitoyltrfase. 
Pfam
 PF01529; zf-DHHC 
SMART
  
PROSITE
 PS50216; ZF_DHHC 
PRINTS