UniProt Accession

 SRP09_HUMAN; P49458; A8K0N0; Q6NVX0; Q8WTW0 

Genbank Protein ID

 U20998; EF488978; AK289595; CH471066; CH471098; CH471098; BC008443; BC067845; BC021995; BC015094; BC022415; BC066957 

Genbank Nucleotide ID

 AAA70170.1; ABP02070.1; BAF82284.1; EAW50106.1; EAW69750.1; EAW69751.1; AAH08443.1; AAH67845.1; AAH21995.1; AAH15094.1; AAH22415.1; AAH66957.1 

Protein Name

 Signal recognition particle 9 kDa protein 

Protein Synonyms/Alias

 SRP9 

Gene Name

 SRP9 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
41	SDGNLCVKVTDDLVR	ubiquitination	[1]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

 Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. 

Sequence Annotation

 MOD_RES 52 52 N6-acetyllysine.  

Keyword

 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Ribonucleoprotein; RNA-binding; Signal recognition particle. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 86 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005785; C:signal recognition particle receptor complex; TAS:ProtInc.
 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; NAS:UniProtKB.
 GO:0008312; F:7S RNA binding; IEA:InterPro.
 GO:0003723; F:RNA binding; TAS:ProtInc.
 GO:0005047; F:signal recognition particle binding; TAS:ProtInc.
 GO:0045900; P:negative regulation of translational elongation; IEA:InterPro.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
 GO:0006412; P:translation; TAS:Reactome. 

Interpro

 IPR008832; Signal_recog_particle_SRP9.
 IPR009018; Signal_recog_particle_SRP9/14. 

Pfam

 PF05486; SRP9-21 

SMART

  

PROSITE

  

PRINTS