| Tag | Content |
|---|
| CPLM ID | CPLM-014811 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | La-related protein 4B |
Protein Synonyms/Alias | La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La-related protein 5 |
Gene Name | Larp4b |
Gene Synonyms/Alias | D13Wsu64e; Kiaa0217; Larp5 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 313 | IKARIKAKAIAINTF | ubiquitination | [1] | | 565 | SLIIGSSKERNLSTD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Stimulates mRNA translation (By similarity). |
Sequence Annotation | DOMAIN 152 241 HTH La-type RNA-binding.
DOMAIN 242 309 RRM.
MOD_RES 426 426 Phosphoserine (By similarity).
MOD_RES 436 436 Phosphoserine (By similarity).
MOD_RES 453 453 Phosphoserine (By similarity).
MOD_RES 500 500 Phosphoserine.
MOD_RES 520 520 Phosphothreonine (By similarity).
MOD_RES 526 526 Phosphoserine (By similarity).
MOD_RES 721 721 Phosphoserine.
MOD_RES 727 727 N6-acetyllysine (By similarity).
MOD_RES 730 730 Phosphoserine (By similarity).
MOD_RES 739 739 Phosphoserine (By similarity). |
Keyword | Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; RNA-binding; Translation regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 741 AA |
Protein Sequence | MTSDQDAKVV AEPQAQRVQE GKDSSHLMNG PISQTTSQTR SLPALTQVPT TKVSELNPNA 60
KVWGTHMLHL EASSAAVGVN AAWEEAPGHP TDCDQQVLGL DANGDGDKSR ENAALPDAQE 120
AEQTDMSTLA LDHSEYEPLP ENNDTGGNES QPESQEDPRE VLKKTLEFCL SRENLASDMY 180
LISQMDSDQY VPITTVANLD HIKKLSTDVD LIVEVLRSLP LVQVDEKGEK VRPNQNRCIV 240
ILREISESTP VEEVEALFKG DNLPKFINCE FAYNDNWFIT FETEADAQQA YKYLREEVRT 300
FQGKPIKARI KAKAIAINTF LPKNGFRPLD MNLYTQQRYA TSFYLPPVYS PQQQFPLYSL 360
ITPQTWSTTH SYLDPPLVTP FPSTGFINGF TSPTFKPATS PLTSLRQYPP RSRNPSKSHL 420
RHAIPSTERG PGLLESPSIF NFTADRLING VRSPQTRQAG QTRTRIQNPS AYAKREIGTG 480
RVEPSSLESS PGLGRGRKNS FGYRKKREEK FTSSQTQSPT PPKPPSPSFE LGLSNFPPLP 540
GAAGNLKTED LFENRLSSLI IGSSKERNLS TDASTNTVPV VGPREPSVPA PCAVSAAFER 600
SPSPVHLPED PKVAEKQRET QSVDRLPSTP TTTACKSVQV NGAATELRKP SYAEICQRTS 660
KDPSSSSPLQ PPKEQKPSTV ACGKEEKQLS EPVERHREPP ALKSTPGVPK DQRRQPGRRA 720
SPPAAGKRLS KEQNTPPKSP Q 741 |
Gene Ontology | GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB. GO:0005829; C:cytosol; ISS:UniProtKB. GO:0042788; C:polysomal ribosome; ISS:UniProtKB. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0045727; P:positive regulation of translation; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |