| Tag | Content |
|---|
| CPLM ID | CPLM-005284 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional regulator AscG |
Protein Synonyms/Alias | Cryptic asc operon repressor |
Gene Name | ascG |
Gene Synonyms/Alias | b2714; JW5434 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 202 | IERLAGYKDALAQHG | acetylation | [1] | | 215 | HGIALNEKLIANGKW | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. |
Sequence Annotation | DOMAIN 2 56 HTH lacI-type.
DNA_BIND 4 23 H-T-H motif (By similarity). |
Keyword | 3D-structure; Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 336 AA |
Protein Sequence | MTTMLEVAKR AGVSKATVSR VLSGNGYVSQ ETKDRVFQAV EESGYRPNLL ARNLSAKSTQ 60
TLGLVVTNTL YHGIYFSELL FHAARMAEEK GRQLLLADGK HSAEEERQAI QYLLDLRCDA 120
IMIYPRFLSV DEIDDIIDAH SQPIMVLNRR LRKNSSHSVW CDHKQTSFNA VAELINAGHQ 180
EIAFLTGSMD SPTSIERLAG YKDALAQHGI ALNEKLIANG KWTPASGAEG VEMLLERGAK 240
FSALVASNDD MAIGAMKALH ERGVAVPEQV SVIGFDDIAI APYTVPALSS VKIPVTEMIQ 300
EIIGRLIFML DGGDFSPPKT FSGKLIRRDS LIAPSR 336 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0043565; F:sequence-specific DNA binding; IDA:EcoCyc. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc. GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc. GO:0006351; P:transcription, DNA-dependent; IEP:EcoCyc. |
Interpro | |
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SMART | |
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PRINTS | |