CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011004
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar GTP-binding protein 1 
Protein Synonyms/Alias
  
Gene Name
 NOG1 
Gene Synonyms/Alias
 YPL093W; LPG15W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
360RINNVLNKIHVAQPQacetylation[1]
383PFIPESVKNLKKYDPacetylation[1]
387ESVKNLKKYDPEDPNacetylation[1]
530KLTKSFGKMEEHMSTacetylation[1]
632HNAVSLSKHLFSGKRacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Involved in the biogenesis of the 60S ribosomal subunit. 
Sequence Annotation
 NP_BIND 174 181 GTP (Potential).
 NP_BIND 220 224 GTP (Potential).
 NP_BIND 288 291 GTP (Potential).
 MOD_RES 563 563 Phosphoserine.  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 647 AA 
Protein Sequence
MQLSWKDIPT VAPANDLLDI VLNRTQRKTP TVIRPGFKIT RIRAFYMRKV KYTGEGFVEK 60
FEDILKGFPN INDVHPFHRD LMDTLYEKNH YKISLAAISR AKSLVEQVAR DYVRLLKFGQ 120
SLFQCKQLKR AALGRMATIV KKLRDPLAYL EQVRQHIGRL PSIDPNTRTL LICGYPNVGK 180
SSFLRCITKS DVDVQPYAFT TKSLYVGHFD YKYLRFQAID TPGILDRPTE EMNNIEMQSI 240
YAIAHLRSCV LYFMDLSEQC GFTIEAQVKL FHSIKPLFAN KSVMVVINKT DIIRPEDLDE 300
ERAQLLESVK EVPGVEIMTS SCQLEENVME VRNKACEKLL ASRIENKLKS QSRINNVLNK 360
IHVAQPQARD DVKRTPFIPE SVKNLKKYDP EDPNRRKLAR DIEAENGGAG VFNVNLKDKY 420
LLEDDEWKND IMPEILDGKN VYDFLDPEIA AKLQALEEEE EKLENEGFYN SDDEEEIYDG 480
FEASEVDDIK EKAAWIRNRQ KTMIAEARNR KSLKNKAIMP RSKLTKSFGK MEEHMSTLGH 540
DMSALQDKQN RAARKNRYVE RGSDVVFGDQ DALTASTENG VKLRQTDRLL DGVADGSMRS 600
KADRMAKMER RERNRHAKQG ESDRHNAVSL SKHLFSGKRG VGKTDFR 647 
Gene Ontology
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0005525; F:GTP binding; ISS:SGD.
 GO:0042273; P:ribosomal large subunit biogenesis; IDA:SGD.
 GO:0000054; P:ribosomal subunit export from nucleus; IPI:SGD.
 GO:0006364; P:rRNA processing; IMP:SGD. 
Interpro
 IPR006073; GTP_binding_domain.
 IPR024926; NOG1.
 IPR010674; NOG1_Rossman_fold_dom.
 IPR012973; NOG_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF06858; NOG1
 PF08155; NOGCT 
SMART
  
PROSITE
  
PRINTS
 PR00326; GTP1OBG.