CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019478
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 714 
Protein Synonyms/Alias
  
Gene Name
 ZNF714 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
100VECKVYKKGYELNQCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 1 47 KRAB.
 ZN_FING 116 138 C2H2-type 1; degenerate.
 ZN_FING 144 166 C2H2-type 2.
 ZN_FING 172 194 C2H2-type 3.
 ZN_FING 200 222 C2H2-type 4.
 ZN_FING 228 250 C2H2-type 5.
 ZN_FING 256 278 C2H2-type 6.
 ZN_FING 284 306 C2H2-type 7.
 ZN_FING 312 334 C2H2-type 8.
 ZN_FING 340 362 C2H2-type 9.
 ZN_FING 368 390 C2H2-type 10.
 ZN_FING 396 418 C2H2-type 11.
 ZN_FING 424 446 C2H2-type 12.
 ZN_FING 452 474 C2H2-type 13.
 ZN_FING 480 502 C2H2-type 14; degenerate.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 554 AA 
Protein Sequence
MNVMLENYKN LVFLAGIAVS KQDPITSLEQ EKEPWNMKIC EMVDESPAMC SSFTRDLWPE 60
QDIKDSFQQV ILRRHGKCEH ENLQLRKGSA NVVECKVYKK GYELNQCLTT TQSKIFPCDK 120
YIKVFHKIFN SNRHKTRHTG EKPFKCKKCD ESFCMLLHLH QHKRIHIREN SYQCEECDKV 180
FKRFSTLTRH KRVHTGEKPF KCEECGKAFK HSSTLTTHKM IHTGEKPYRC EECGKAFYHS 240
SHLTTHKVIH TGEKPFKCEE CGKAFNHPSA LTTHKFIHVK EKPYKCEECD KAFNRFSYLT 300
KHKIIHSGEK SYKCEQCGKG FNWSSTLTKH KRIHTGEKPY KCEECGKAFN VSSHLTTHKM 360
IHTGEKPYKC EECGKAFNHS SKLTIHKIIH TGEKPYKCEE CGKAFNQSSN LTKHKIIHTG 420
EKLYKCEECG KAFNRSSNLT THKRIHTGEK PYKCEECGKA FNRSSNLTKH NIIHTGEKSY 480
KCEECGKAFN QSSTLTKHRK IQQGMVAHAC NPNTLRGLGE QIARSGVQDQ PGQHGKTPSL 540
LKIQKFAGCG GRRL 554 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS