CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024191
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lysine--tRNA ligase 
Protein Synonyms/Alias
 Lysyl-tRNA synthetase; LysRS 
Gene Name
 At3g11710; T19F11.11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
10GAADQTTKALSELAMacetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 626 AA 
Protein Sequence
MEGAADQTTK ALSELAMDSS TTLNAAESSA GDGAGPRSKN ALKKEQKMKQ KEEEKRRKDE 60
EKAEKAKQAP KASSQKAVAA DDEEMDATQY YENRLKYLAA EKAKGENPYP HKFAVSMSIP 120
KYIETYGSLN NGDHVENAEE SLAGRIMSKR SSSSKLFFYD LHGDDFKVQV MADASKSGLD 180
EAEFLKLHSN AKRGDIVGVI GFPGKTKRGE LSIFPRSFIL LSHCLHMMPR KADNVNAKKP 240
EIWVPGQTRN PEAYVLKDQE SRYRQRHLDM ILNVEVRQIF RTRAKIISYV RRFLDNKNFL 300
EVETPMMNMI AGGAAARPFV THHNDLDMRL YMRIAPELYL KQLIVGGLER VYEIGKQFRN 360
EGIDLTHNPE FTTCEFYMAF ADYNDLMEMT EVMLSGMVKE LTGGYKIKYN ANGYDKDPIE 420
IDFTPPFRRI EMIGELEKVA KLNIPKDLAS EEANKYLIDA CARFDVKCPP PQTTARLLDK 480
LVGEFLEPTC VNPTFIINQP EIMSPLAKWH RSKSGLTERF ELFINKHELC NAYTELNDPV 540
VQRQRFADQL KDRQSGDDEA MALDETFCNA LEYGLAPTGG WGLGIDRLSM LLTDSLNIKE 600
VLFFPAMRPP QEESAAAQAP LTEEKK 626 
Gene Ontology
 GO:0005829; C:cytosol; IDA:TAIR.
 GO:0009506; C:plasmodesma; IDA:TAIR.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004824; F:lysine-tRNA ligase activity; IDA:TAIR.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006430; P:lysyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR004364; aa-tRNA-synt_II.
 IPR018150; aa-tRNA-synt_II-like.
 IPR006195; aa-tRNA-synth_II.
 IPR002313; Lys-tRNA-ligase_II.
 IPR018149; Lys-tRNA-synth_II_C.
 IPR012340; NA-bd_OB-fold.
 IPR004365; NA-bd_OB_tRNA-helicase. 
Pfam
 PF00152; tRNA-synt_2
 PF01336; tRNA_anti 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II 
PRINTS
 PR00982; TRNASYNTHLYS.