UniProt Accession

 Q7KNM2_DROME; Q7KNM2 

Genbank Protein ID

 AF030443; AF030444; AF106664; AF218861; AE014134; AY060944; AY113433; AE014134; AE014134; AE014134; AB017606; AB017607 

Genbank Nucleotide ID

 AAC38964.1; AAC38965.1; AAD21970.1; AAF31701.1; AAF51487.1; AAL28492.1; AAM29438.1; AAN10499.1; AGB92370.1; AGB92371.1; BAA34574.1; BAA34575.1 

Protein Name

 Dorsal interacting protein 4 

Protein Synonyms/Alias

 GM08377p; Lesswright, isoform A; Lesswright, isoform B; Lesswright, isoform C; Lesswright, isoform D; RE25737p; Ubiquitin-conjugating enzyme; Ubiquitin-conjugating enzyme 9; Ubiquitin-conjugating enzyme 9 homolog 

Gene Name

 lwr 

Gene Synonyms/Alias

 semi; UBC9; Ubc9; CG3018; Dmel_CG3018 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
65	YKLRMIFKDDYPTSP	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Ligase; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 159 AA 

Protein Sequence

Gene Ontology

 GO:0000940; C:condensed chromosome outer kinetochore; IDA:FlyBase.
 GO:0000780; C:condensed nuclear chromosome, centromeric region; IDA:FlyBase.
 GO:0019789; F:SUMO ligase activity; IGI:FlyBase.
 GO:0071560; P:cellular response to transforming growth factor beta stimulus; IGI:FlyBase.
 GO:0007391; P:dorsal closure; IMP:FlyBase.
 GO:0016321; P:female meiosis chromosome segregation; IGI:FlyBase.
 GO:0035172; P:hemocyte proliferation; IMP:FlyBase.
 GO:0006959; P:humoral immune response; IMP:FlyBase.
 GO:0007095; P:mitotic G2 DNA damage checkpoint; IGI:FlyBase.
 GO:0035207; P:negative regulation of hemocyte proliferation; IMP:FlyBase.
 GO:0035204; P:negative regulation of lamellocyte differentiation; IMP:FlyBase.
 GO:0045751; P:negative regulation of Toll signaling pathway; IMP:FlyBase.
 GO:0006606; P:protein import into nucleus; IMP:FlyBase.
 GO:0016925; P:protein sumoylation; IMP:FlyBase.
 GO:0007352; P:zygotic specification of dorsal/ventral axis; IGI:FlyBase. 

Interpro

 IPR027230; Ubc9.
 IPR000608; UBQ-conjugat_E2.
 IPR023313; UBQ-conjugating_AS.
 IPR016135; UBQ-conjugating_enzyme/RWD. 

Pfam

 PF00179; UQ_con 

SMART

  

PROSITE

 PS00183; UBIQUITIN_CONJUGAT_1
 PS50127; UBIQUITIN_CONJUGAT_2 

PRINTS