| Tag | Content |
|---|
| CPLM ID | CPLM-004526 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 43 |
Protein Synonyms/Alias | Zinc finger protein 39; Zinc finger protein HTF6; Zinc finger protein KOX27 |
Gene Name | ZNF43 |
Gene Synonyms/Alias | KOX27; ZNF39; ZNF39L1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 306 | SNLTEHKKIHPGEKP | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 7 75 KRAB.
ZN_FING 174 196 C2H2-type 1.
ZN_FING 202 224 C2H2-type 2; degenerate.
ZN_FING 230 252 C2H2-type 3; degenerate.
ZN_FING 258 280 C2H2-type 4; degenerate.
ZN_FING 286 308 C2H2-type 5.
ZN_FING 314 336 C2H2-type 6.
ZN_FING 342 364 C2H2-type 7.
ZN_FING 370 392 C2H2-type 8.
ZN_FING 398 420 C2H2-type 9.
ZN_FING 426 448 C2H2-type 10.
ZN_FING 454 476 C2H2-type 11.
ZN_FING 482 504 C2H2-type 12.
ZN_FING 510 532 C2H2-type 13.
ZN_FING 538 560 C2H2-type 14.
ZN_FING 566 588 C2H2-type 15.
ZN_FING 594 616 C2H2-type 16.
ZN_FING 622 644 C2H2-type 17.
ZN_FING 650 672 C2H2-type 18.
ZN_FING 678 700 C2H2-type 19.
ZN_FING 706 728 C2H2-type 20.
ZN_FING 734 756 C2H2-type 21.
ZN_FING 762 784 C2H2-type 22. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 809 AA |
Protein Sequence | MGPLTFMDVA IEFCLEEWQC LDIAQQNLYR NVMLENYRNL VFLGIAVSKP DLITCLEQEK 60
EPWEPMRRHE MVAKPPVMCS HFTQDFWPEQ HIKDPFQKAT LRRYKNCEHK NVHLKKDHKS 120
VDECKVHRGG YNGFNQCLPA TQSKIFLFDK CVKAFHKFSN SNRHKISHTE KKLFKCKECG 180
KSFCMLPHLA QHKIIHTRVN FCKCEKCGKA FNCPSIITKH KRINTGEKPY TCEECGKVFN 240
WSSRLTTHKK NYTRYKLYKC EECGKAFNKS SILTTHKIIR TGEKFYKCKE CAKAFNQSSN 300
LTEHKKIHPG EKPYKCEECG KAFNWPSTLT KHKRIHTGEK PYTCEECGKA FNQFSNLTTH 360
KRIHTAEKFY KCTECGEAFS RSSNLTKHKK IHTEKKPYKC EECGKAFKWS SKLTEHKLTH 420
TGEKPYKCEE CGKAFNWPST LTKHNRIHTG EKPYKCEVCG KAFNQFSNLT THKRIHTAEK 480
PYKCEECGKA FSRSSNLTKH KKIHIEKKPY KCEECGKAFK WSSKLTEHKI THTGEKPYKC 540
EECGKAFNHF SILTKHKRIH TGEKPYKCEE CGKAFTQSSN LTTHKKIHTG EKFYKCEECG 600
KAFTQSSNLT THKKIHTGGK PYKCEECGKA FNQFSTLTKH KIIHTEEKPY KCEECGKAFK 660
WSSTLTKHKI IHTGEKPYKC EECGKAFKLS STLSTHKIIH TGEKPYKCEK CGKAFNRSSN 720
LIEHKKIHTG EQPYKCEECG KAFNYSSHLN THKRIHTKEQ PYKCKECGKA FNQYSNLTTH 780
NKIHTGEKLY KPEDVTVILT TPQTFSNIK 809 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; TAS:ProtInc. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |