CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038042
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 C-Jun-amino-terminal kinase-interacting protein 4 
Protein Synonyms/Alias
  
Gene Name
 Spag9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
55NLPRILRKERPISLGubiquitination[1]
90TPGSEQWKFQELSQPubiquitination[1]
501FGWSLPQKYKQVANGacetylation[2]
1075HGHRDAVKFFVAVPGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1169 AA 
Protein Sequence
MNPGCMLLFV FGFVGGAVVI NSAILVSLSV LLLVHFSIST GVPALTQNLP RILRKERPIS 60
LGIFPLPAGD GLLTPDTQKG GETPGSEQWK FQELSQPRSH TSLKDELSDI SQGGSKATTP 120
ASTANSDVSA IPPDTPSKED NEGFVKGTDT SNKSEISKHI EVQVAQETRN VSTESGENEE 180
KSEVQAIIES TPELDMDKDL SGYKGSSTPT KGIENKAFDR NTESLFEELS SAGSGLIGDV 240
DEGADLLDHN FFGMGREVEN LILENTQLLE TKNALNVVKN DLIAKVDELT CEKDVLQGEL 300
EAVKQAKLKL EDKNRELEEE LRKARAEAED ARQKAKDDDD SDIPTAQRKR FTRVEMARVL 360
MERNQYKERL MELQEAVRWT EMIRASRENP AMQEKKRSSI WQFFSRLFSS SSNATKKPEP 420
PVNLKYNAPT SHVTPSVKKR SSTLSQLPGD KSKAFDFLSE ETEASLASRR EQKREQYRQV 480
KAHVQKEDGR VQAFGWSLPQ KYKQVANGQG ETKMKNLPVP VYLRPLDEKD ASMKLWCAVG 540
VNLSGGKTRD GGSVVGASVF YKDIAGLDTE GSKQRSASQS SLDKLDQELK EQQKEFKNQE 600
ELSSQVWICT STHSTTKVII IDAVQPGNIL DSFTVCNSHV LCIASVPGAR ETDYPAGEEL 660
SESGQVDKAS LCGSMTSNSS AEMDSLLGGI TVVGCSTEGL TGAATSPSTN GASPVIEKPP 720
EMETENSEVD ENIPTAEEAT EATEGNAGST EDTVDISQPG VYTEHVFTDP LGVQIPEDLS 780
PVFQSSNDSD VYKDQISVLP NEQDLAREEA QKMSSLLPTM WLGAQNGCLY VHSSVAQWRK 840
CLHSIKLKDS ILSIVHVKGI VLVALADGTL AIFHRGVDGQ WDLSNYHLLD LGRPHHSIRC 900
MTVVHDKVWC GYRNKIYVVQ PKAMKIEKSF DAHPRKESQV RQLAWVGDGV WVSIRLDSTL 960
RLYHAHTYQH LQDVDIEPYV SKMLGTGKLG FSFVRITALM VSCNRLWVGT GNGVIISIPL 1020
TETNKTSGTP GNRPGSVIRV YGDENSDKVT PGTFIPYCSM AHAQLCFHGH RDAVKFFVAV 1080
PGQVISPQSS SGGADLTADK AGSSAQEPSS QTPLKSMLVI SGGEGYIDFR MGDEGGESEL 1140
LGEDLPLEPS VTKAERSHLI VWQVMCGNE 1169 
Gene Ontology
 GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
 GO:0008432; F:JUN kinase binding; IDA:MGI.
 GO:0019894; F:kinesin binding; IDA:MGI.
 GO:0048273; F:mitogen-activated protein kinase p38 binding; IDA:MGI.
 GO:0007257; P:activation of JUN kinase activity; IDA:MGI.
 GO:0090074; P:negative regulation of protein homodimerization activity; IDA:MGI.
 GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.
 GO:0051260; P:protein homooligomerization; IDA:MGI.
 GO:0051146; P:striated muscle cell differentiation; IGI:MGI. 
Interpro
 IPR011044; Quino_amine_DH_bsu.
 IPR015943; WD40/YVTN_repeat-like_dom. 
Pfam
  
SMART
  
PROSITE
  
PRINTS