UniProt Accession

 EFP_MYCPN; P75085 

Genbank Protein ID

 U00089 

Genbank Nucleotide ID

 AAB95773.1 

Protein Name

 Elongation factor P 

Protein Synonyms/Alias

 EF-P 

Gene Name

 efp 

Gene Synonyms/Alias

 MPN_029; MP125 

Created Date

 July 27, 2013 

Organism

 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 

NCBI Taxa ID

 272634 

Lysine Modification

Position	Peptide	Type	References
8	MADMIEAKSLRSGQT	acetylation	[1]

Reference

 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 

Functional Description

 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 190 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003746; F:translation elongation factor activity; IEA:HAMAP.
 GO:0043043; P:peptide biosynthetic process; IEA:InterPro. 

Interpro

 IPR015365; Elong-fact-P_C.
 IPR012340; NA-bd_OB-fold.
 IPR014722; Rib_L2_dom2.
 IPR020599; Transl_elong_fac_P/YeiP.
 IPR013185; Transl_elong_KOW-like.
 IPR001059; Transl_elong_P/YeiP_cen.
 IPR013852; Transl_elong_P/YeiP_CS.
 IPR011768; Transl_elongation_fac_P.
 IPR008991; Translation_prot_SH3-like. 

Pfam

 PF01132; EFP
 PF08207; EFP_N
 PF09285; Elong-fact-P_C 

SMART

 SM00841; Elong-fact-P_C 

PROSITE

 PS01275; EFP 

PRINTS