| Tag | Content |
|---|
| CPLM ID | CPLM-000544 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | CD166 antigen |
Protein Synonyms/Alias | Activated leukocyte cell adhesion molecule; HB2; KG-CAM; Protein MEMD; SB-10 antigen; CD166 |
Gene Name | Alcam |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 152 | FLETEQLKKLGDCIS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. May be involved in osteogenesis. May play an important role in the development of a variety of mesenchymal tissues (By similarity). |
Sequence Annotation | DOMAIN 28 120 Ig-like V-type 1.
DOMAIN 125 234 Ig-like V-type 2.
DOMAIN 245 328 Ig-like C2-type 1.
DOMAIN 333 409 Ig-like C2-type 2.
DOMAIN 416 501 Ig-like C2-type 3.
CARBOHYD 95 95 N-linked (GlcNAc...) (Potential).
CARBOHYD 167 167 N-linked (GlcNAc...) (Potential).
CARBOHYD 265 265 N-linked (GlcNAc...) (Potential).
CARBOHYD 306 306 N-linked (GlcNAc...) (Potential).
CARBOHYD 361 361 N-linked (GlcNAc...) (Potential).
CARBOHYD 457 457 N-linked (GlcNAc...) (Potential).
CARBOHYD 480 480 N-linked (GlcNAc...) (Potential).
CARBOHYD 499 499 N-linked (GlcNAc...) (Potential).
DISULFID 43 113 Potential.
DISULFID 157 220 Potential.
DISULFID 270 313 Potential.
DISULFID 354 392 Potential.
DISULFID 435 485 Potential. |
Keyword | Cell adhesion; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 583 AA |
Protein Sequence | MASKGSPSCR LVFCLLISAA VLRPGLGWYT VNSAYGDTIV MPCRLDVPQN LMFGKWKYEK 60
PDGSPVFIAF RSSTKKSVQY DDVPEYKDRL SLSENYTLSI NNAKISDEKR FVCMLVTEDN 120
VFEAPTLVKV FKQPSKPEIV NRAAFLETEQ LKKLGDCISR DSYPDGNITW YRNGKVLQPV 180
DGEVSILFKK EIDPGTQLYT MTSSLEYKTT KSDIQMPFTC SVTYYGPSGQ KTIYSEQAIF 240
DIYYPTEQVT IQVLPPKNAI KEGDNITLQC LGNGNPPPEE FMFYLPGQAE GIRSSNTYTL 300
TDVRRNATGD YKCSLIDQRN MAASTTITVH YLDLSLNPSG EVTKQIGDTL PVSCTISASR 360
NATVVWMKDN IRLRSSPSFS SLHYQDAGNY VCETALQEVE GLKKRESLTL IVEGKPQIKM 420
TKKTDPSGLS KTIICHVEGF PKPAIQWTIT GSGSVINQTE ESPYINGRYY SKIIISPEEN 480
VTLTCTAENQ LERTVNSLNV SAISIPEHDE ADDISDENRE KVNDQAKLIV GIVVGLLLAA 540
LVAGVVYWLY MKKSKTASKH VNKDLGNMEE NKKLEENNHK TEA 583 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |