CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017424
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DnaJ homolog subfamily C member 22 
Protein Synonyms/Alias
  
Gene Name
 DNAJC22 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
170AQRHRRYKALVASEPubiquitination[1]
274VHSFQDEKRQLAYQVubiquitination[1]
302RSYQELVKVWHPDHNubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 May function as a co-chaperone. 
Sequence Annotation
 DOMAIN 277 341 J.  
Keyword
 Chaperone; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 341 AA 
Protein Sequence
MAKGLLVTYA LWAVGGPAGL HHLYLGRDSH ALLWMLTLGG GGLGWLWEFW KLPSFVAQAN 60
RAQGQRQSPR GVTPPLSPIR FAAQVIVGIY FGLVALISLS SMVNFYIVAL PLAVGLGVLL 120
VAAVGNQTSD FKNTLGSAFL TSPIFYGRPI AILPISVAAS ITAQRHRRYK ALVASEPLSV 180
RLYRLGLAYL AFTGPLAYSA LCNTAATLSY VAETFGSFLN WFSFFPLLGR LMEFVLLLPY 240
RIWRLLMGET GFNSSCFQEW AKLYEFVHSF QDEKRQLAYQ VLGLSEGATN EEIHRSYQEL 300
VKVWHPDHNL DQTEEAQRHF LEIQAAYEVL SQPRKPWGSR R 341 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR001623; DnaJ_domain.
 IPR007829; TM2. 
Pfam
 PF00226; DnaJ
 PF05154; TM2 
SMART
 SM00271; DnaJ 
PROSITE
 PS00636; DNAJ_1
 PS50076; DNAJ_2 
PRINTS
 PR00625; JDOMAIN.