CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030844
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heterogeneous nuclear ribonucleoprotein H3 
Protein Synonyms/Alias
 cDNA FLJ57726, highly similar to Heterogeneous nuclear ribonucleoprotein H3 
Gene Name
 HNRNPH3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
6**MDWVMKHNGPNDAubiquitination[1, 2, 3, 4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Ribonucleoprotein; Viral nucleoprotein; Virion. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 238 AA 
Protein Sequence
MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGYG GFDDYGGYNN YGYGNDGFDD 60
RMRDGRGMGG HGYGGAGDAS SGFHGGHFVH MRGLPFRATE NDIANFFSPL NPIRVHIDIG 120
ADGRATGEAD VEFVTHEDAV AAMSKDKNNM QHRYIELFLN STPGGGSGMG GSGMGGYGRD 180
GMDNQGGYGS VGRMGMGNNY SGGYGTPDGL GGYGRGGGGS GGYYGQGGMS GGGWRGMY 238 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS