| Tag | Content |
|---|
| CPLM ID | CPLM-014841 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | KAT8 regulatory NSL complex subunit 2 |
Protein Synonyms/Alias | NSL complex protein NSL2; Non-specific lethal 2 homolog |
Gene Name | Kansl2 |
Gene Synonyms/Alias | Nsl2 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 481 | GLATANGKPEPTSIS | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription (By similarity). |
Sequence Annotation | MOD_RES 147 147 Phosphoserine (By similarity).
MOD_RES 149 149 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Chromatin regulator; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 488 AA |
Protein Sequence | MNRIRIHVLP TNRGRITPVP RSQEPLSCSF THRPCSQPRL EGQEFCLKHI LEDKNAPFKQ 60
CSYISTKNGK RCPSAAPKPE KKDGVSFCAE HARRNALALH AQMKKSNPGP MGETLLCQLS 120
SYAKTELGSQ TPESSRSEAS RILDEDSWSD GDQEPITVDQ TWRGDPDSEA DSIDSDQEDP 180
LKHAGVYTAE EVALIMREKL IRLQSLYIDQ FKRLQHLLKE KKRRYLHNRK VEHEALGSSL 240
LTGPEGLLAK ERENLKRLKC LRRYRQRYGV EALLHRQLKE RRMLATEGAA QQAHTTRSSQ 300
RCLAFVDDVR CSNQSLPMTR HCLTHICQDT NQVLFKCCQG SEEVPCNKPV PVSLSEDPCC 360
PLHFQLPPQM YKPEQVLSVP DGLEAGPMDL YLSAAELQPT ESLPLELSDD LDVVGDGMPC 420
PPSPLLFDPS LTLEDHSVTE IAGGPGQIQV AGDGCRSQGP HNVEKTCAPF PQRGLATANG 480
KPEPTSIS 488 |
Gene Ontology | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB. GO:0046972; F:histone acetyltransferase activity (H4-K16 specific); IEA:Compara. GO:0043995; F:histone acetyltransferase activity (H4-K5 specific); IEA:Compara. GO:0043996; F:histone acetyltransferase activity (H4-K8 specific); IEA:Compara. GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB. GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB. GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |