UniProt Accession

 E7EUS7_HUMAN; E7EUS7 

Genbank Protein ID

 AC008957; AC010631 

Genbank Nucleotide ID

  

Protein Name

 Excitatory amino acid transporter 1 

Protein Synonyms/Alias

  

Gene Name

 SLC1A3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
79	RMSYREVKYFSFPGE	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 101 AA 

Protein Sequence

Gene Ontology

 GO:0042995; C:cell projection; IEA:Compara.
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0043205; C:fibril; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0016595; F:glutamate binding; IEA:Compara.
 GO:0005314; F:high-affinity glutamate transmembrane transporter activity; IEA:Compara.
 GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
 GO:0031223; P:auditory behavior; IEA:Compara.
 GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Compara.
 GO:0021545; P:cranial nerve development; IEA:Compara.
 GO:0009449; P:gamma-aminobutyric acid biosynthetic process; IEA:Compara.
 GO:0006537; P:glutamate biosynthetic process; IEA:Compara.
 GO:0051938; P:L-glutamate import; IEA:Compara.
 GO:0050885; P:neuromuscular process controlling balance; IEA:Compara.
 GO:0050806; P:positive regulation of synaptic transmission; IEA:Compara.
 GO:0046677; P:response to antibiotic; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0009416; P:response to light stimulus; IEA:Compara.
 GO:0009611; P:response to wounding; IEA:Compara.
 GO:0007605; P:sensory perception of sound; IEA:Compara. 

Interpro

 IPR001991; Na-dicarboxylate_symporter.
 IPR018107; Na-dicarboxylate_symporter_CS. 

Pfam

 PF00375; SDF 

SMART

  

PROSITE

 PS00713; NA_DICARBOXYL_SYMP_1 

PRINTS

 PR00173; EDTRNSPORT.