CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028750
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 1 (Glial high affinity glutamate transporter), member 2 
Protein Synonyms/Alias
 Solute carrier family 1 (Glial high affinity glutamate transporter), member 2, isoform CRA_a 
Gene Name
 Slc1a2 
Gene Synonyms/Alias
 mCG_9657; RP23-163L4.1-002 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
9VSANNMPKQVEVRMHubiquitination[1]
26HLSSDEPKHRNLGMRubiquitination[1]
155KQLGPGKKNDEVSSLubiquitination[1]
379EDNLGIDKRVTRFVLubiquitination[1]
494GIVYHLSKSELDTIDubiquitination[1]
514QEDIEMTKTQSIYDDubiquitination[1]
522TQSIYDDKNHRESNSubiquitination[1]
554VTLAANGKSADCSVEubiquitination[1]
566SVEEEPWKREK****ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 569 AA 
Protein Sequence
MVSANNMPKQ VEVRMHDSHL SSDEPKHRNL GMRMCDKLGK NLLLSLTVFG VILGAVCGGL 60
LRLASPIHPD VVMLIAFPGD ILMRMLKMLI LPLIISSLIT GLSGLDAKAS GRLGTRAMVY 120
YMSTTIIAAV LGVILVLAIH PGNPKLKKQL GPGKKNDEVS SLDAFLDLIR NLFPENLVQA 180
CFQQIQTVTK KVLVAPPSEE ANTTKAVISM LNETMNEAPE ETKIVIKKGL EFKDGMNVLG 240
LIGFFIAFGI AMGKMGEQAK LMVEFFNILN EIVMKLVIMI MWYSPLGIAC LICGKIIAIK 300
DLEVVARQLG MYMITVIVGL IIHGGIFLPL IYFVVTRKNP FSFFAGIFQA WITALGTASS 360
AGTLPVTFRC LEDNLGIDKR VTRFVLPVGA TINMDGTALY EAVAAIFIAQ MNGVILDGGQ 420
IVTVSLTATL ASIGAASIPS AGLVTMLLIL TAVGLPTEDI SLLVAVDWLL DRMRTSVNVV 480
GDSFGAGIVY HLSKSELDTI DSQHRMQEDI EMTKTQSIYD DKNHRESNSN QCVYAAHNSV 540
VIDECKVTLA ANGKSADCSV EEEPWKREK 569 
Gene Ontology
 GO:0030673; C:axolemma; IDA:MGI.
 GO:0005887; C:integral to plasma membrane; IC:MGI.
 GO:0015501; F:glutamate:sodium symporter activity; IDA:MGI.
 GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
 GO:0030534; P:adult behavior; IMP:MGI.
 GO:0031668; P:cellular response to extracellular stimulus; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0010259; P:multicellular organismal aging; IMP:MGI.
 GO:0046326; P:positive regulation of glucose import; IMP:MGI.
 GO:0043200; P:response to amino acid stimulus; IMP:MGI.
 GO:0042493; P:response to drug; IMP:MGI.
 GO:0009611; P:response to wounding; IMP:MGI.
 GO:0021537; P:telencephalon development; IMP:MGI.
 GO:0007632; P:visual behavior; IMP:MGI. 
Interpro
 IPR001991; Na-dicarboxylate_symporter.
 IPR018107; Na-dicarboxylate_symporter_CS. 
Pfam
 PF00375; SDF 
SMART
  
PROSITE
 PS00713; NA_DICARBOXYL_SYMP_1
 PS00714; NA_DICARBOXYL_SYMP_2 
PRINTS
 PR00173; EDTRNSPORT.