CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020685
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serum response factor-binding protein 1 
Protein Synonyms/Alias
 SRF-dependent transcription regulation-associated protein; p49/STRAP 
Gene Name
 Srfbp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
435KIAVFQGKKITFDD*acetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells. 
Sequence Annotation
 MOD_RES 214 214 Phosphoserine (By similarity).
 MOD_RES 276 276 Phosphoserine (By similarity).
 MOD_RES 291 291 Phosphoserine (By similarity).
 MOD_RES 293 293 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 441 AA 
Protein Sequence
MAADPLPPSA MVQPGTLNLN NEVVKMRKEV KRIRVLVIRK LVRSVGRLKS KKGTEDALLK 60
NQRRAQRLLE EIHAMKELKP DVVTKSALSD DINFEKTCKK PDSTATDRAV ARLAGHPLLK 120
KKIDVLKDAV QAFKDARQSA PAAESSESTS GEGRCKDIAR SKDDARESQH PERTVVREQK 180
AKDTNTAAKN AASGSKEKLA KTEQAPRAGT TPGSQGRPSG KGAGVNSEHQ GAPAPGDSNQ 240
GKASTKTPED SVCEPANNGV SEEEESEGEK EYFDDSTEER FYKQSSASED SDSGDDFFIG 300
KVRRTRKKES GVHSSAKELK PLPKVPSKTS TLETPWDVRN DKHRPIPEAR KFESVFFHSL 360
AGPKSSRRDP REQAPKNKAP DFPENEPPVK KQFTKSAYRG FESVKQTMQA PLHPSWEASR 420
RRKEQQSKIA VFQGKKITFD D 441 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR015158; Bud-site_select_BUD22. 
Pfam
 PF09073; BUD22 
SMART
  
PROSITE
  
PRINTS