Tag | Content |
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CPLM ID | CPLM-005226 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Beta-galactosidase |
Protein Synonyms/Alias | Acid beta-galactosidase; Lactase |
Gene Name | Glb1 |
Gene Synonyms/Alias | Bgl; Glb-1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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347 | EAGDLTKKYFALREV | acetylation | [1] | 377 | TPKFAYGKVALRKFK | acetylation | [1] |
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Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. |
Sequence Annotation | ACT_SITE 189 189 Proton donor (Potential). ACT_SITE 269 269 Nucleophile (Potential). CARBOHYD 27 27 N-linked (GlcNAc...) (Potential). CARBOHYD 248 248 N-linked (GlcNAc...) (Potential). CARBOHYD 500 500 N-linked (GlcNAc...) (Potential). CARBOHYD 504 504 N-linked (GlcNAc...) (Potential). CARBOHYD 510 510 N-linked (GlcNAc...) (Potential). CARBOHYD 544 544 N-linked (GlcNAc...) (Potential). CARBOHYD 557 557 N-linked (GlcNAc...) (Potential). CARBOHYD 617 617 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Glycosidase; Hydrolase; Lysosome; Reference proteome; Signal; Zymogen. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 647 AA |
Protein Sequence | MLRVPLCTPL PLLALLQLLG AAHGIYNVTQ RTFKLDYSRD RFLKDGQPFR YISGSIHYFR 60 IPRFYWEDRL LKMKMAGLNA IQMYVPWNFH EPQPGQYEFS GDRDVEHFIQ LAHELGLLVI 120 LRPGPYICAE WDMGGLPAWL LEKQSIVLRS SDPDYLVAVD KWLAVLLPKM KPLLYQNGGP 180 IITVQVENEY GSYFACDYDY LRFLVHRFRY HLGNDVILFT TDGASEKMLK CGTLQDLYAT 240 VDFGTGNNIT QAFLVQRKFE PKGPLINSEF YTGWLDHWGK PHSTVKTKTL ATSLYNLLAR 300 GANVNLYMFI GGTNFAYWNG ANTPYEPQPT SYDYDAPLSE AGDLTKKYFA LREVIQMFKE 360 VPEGPIPPST PKFAYGKVAL RKFKTVAEAL GILCPNGPVK SLYPLTFTQV KQYFGYVLYR 420 TTLPQDCSNP KPIFSSPFNG VRDRAYVSVD GVPQGILDRN LMTALNIRGK AGATLDILVE 480 NMGRVNYGRF INDFKGLISN MTINSTVLTN WTVFPLNTEA MVRNHLWGRE ASDEGHLDGR 540 STSNSSDLIL PTFYVGNFSI PSGIPDLPQD TFIQFPGWSK GQVWINGFNL GRYWPTMGPQ 600 KTLFVPRNIL TTSAPNNITV LELEFAPCSE GTPELCTVEF VDTPVIS 647 |
Gene Ontology | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell. GO:0004565; F:beta-galactosidase activity; IDA:MGI. GO:0016936; F:galactoside binding; IEA:Compara. GO:0019388; P:galactose catabolic process; IEA:Compara. |
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