CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010373
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Triosephosphate isomerase 
Protein Synonyms/Alias
 TIM; Triose-phosphate isomerase 
Gene Name
 tpiA 
Gene Synonyms/Alias
 tim; tpi; MPN_629; MP213 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
11KYLIGNWKTNKDLHQacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819
Functional Description
  
Sequence Annotation
 ACT_SITE 93 93 Electrophile (By similarity).
 ACT_SITE 160 160 Proton acceptor (By similarity).
 BINDING 9 9 Substrate (By similarity).
 BINDING 11 11 Substrate (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase; Pentose shunt; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 244 AA 
Protein Sequence
MRTKYLIGNW KTNKDLHQAL AFVEQFKQHP AKTKAVLGIA PVHVHLTEVN KVLPNNLLLL 60
AQDANFIASG SYTGTVSYTQ LQDIKVNSVI IGHSERRKYF NETAQVINQK LKACLQAGML 120
VVLCIGETEG QPISFLKEDL TQVLQGIDLS LLKQLVIAYE PIWAIGTGKT ATPEIANNTI 180
AQIRVYLSEL YNKEIAQQTS ILYGGSVAKD NIKELAQTEQ IDGFLVGKAS LDVNDFLVMA 240
QVYA 244 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004807; F:triose-phosphate isomerase activity; IEA:HAMAP.
 GO:0006094; P:gluconeogenesis; IEA:HAMAP.
 GO:0006096; P:glycolysis; IEA:HAMAP.
 GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR022896; TrioseP_Isoase_bac/euk.
 IPR000652; Triosephosphate_isomerase.
 IPR020861; Triosephosphate_isomerase_AS. 
Pfam
 PF00121; TIM 
SMART
  
PROSITE
 PS00171; TIM_1
 PS51440; TIM_2 
PRINTS