CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034155
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Cyp3a57 
Protein Synonyms/Alias
  
Gene Name
 Cyp3a57 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
96IIKIVLVKECYSVFTubiquitination[1]
143TFTSSKLKEMFPIMRubiquitination[1]
266DRLDYNQKNRVDFLQubiquitination[1]
330THPDVQKKLQDEIDRubiquitination[1]
421FCPERFSKENKGNIDubiquitination[1]
424ERFSKENKGNIDPYIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MELIPNLSIQ TWVLLVTSLV FFYIYGTYSH GLFKKLGIPG PKPLPLFGNI INYLDGMWKF 60
DDDCYKKYGK IWGFYEGPQP ILAIMDPEII KIVLVKECYS VFTNRRPFGP VGFLKKSITI 120
SEDEEWKRLR TLLSPTFTSS KLKEMFPIMR QYGDILVRNL RREEEKEEPI NMKDIFGAYS 180
MDVITGTSCG VNIDSLNNPQ DPFVQKIKKI LKFKFFDPFL LSVVLFPFLT PIYEMLNLSI 240
FPRQSMNFFK KFVKKMKKDR LDYNQKNRVD FLQLMMNTQN SKGQESLKAL SDLEMAAQTL 300
IFIFGGYDGT STSISFIMYE LATHPDVQKK LQDEIDRALP NKAPVTYDAL MDMEYLDMVV 360
NESLRLYPVV SRIDRFSKKD VEIHGVFIPK GTIVMIPIYP LHRDPEYWPE PEDFCPERFS 420
KENKGNIDPY IYMPFGNGPR NCIGMRFALI SVKLAVTGVL QNFTVQPCEE TQIPVKISRQ 480
PIFRPEKPII LKFVSRDKPR TGP 503 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR008072; Cyt_P450_E_CYP3A.
 IPR002402; Cyt_P450_E_grp-II. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00464; EP450II.
 PR01689; EP450IICYP3A.
 PR00385; P450.