| Tag | Content |
|---|
| CPLM ID | CPLM-024486 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 860 |
Protein Synonyms/Alias | |
Gene Name | ZNF860 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 265 | YKCDVCGKVFNQKRY | ubiquitination | [1] | | 315 | HTGEKPYKCEECDKV | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation (By similarity). |
Sequence Annotation | DOMAIN 24 99 KRAB.
ZN_FING 230 252 C2H2-type 1; degenerate.
ZN_FING 258 280 C2H2-type 2.
ZN_FING 286 308 C2H2-type 3.
ZN_FING 314 336 C2H2-type 4.
ZN_FING 342 364 C2H2-type 5.
ZN_FING 370 392 C2H2-type 6.
ZN_FING 398 420 C2H2-type 7.
ZN_FING 426 448 C2H2-type 8.
ZN_FING 454 476 C2H2-type 9.
ZN_FING 482 504 C2H2-type 10.
ZN_FING 510 532 C2H2-type 11.
ZN_FING 538 560 C2H2-type 12.
ZN_FING 566 588 C2H2-type 13; degenerate.
ZN_FING 594 616 C2H2-type 14. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 632 AA |
Protein Sequence | MLREEAAQKR KEKEPGMALP QGHLTFRDVA IEFSLEEWKC LDPTQRALYR AMMLENYRNL 60
HSVDISSKCM MKKFSSTAQG NTEVDTGTLE RHESHHIGDF CFQKIGKDIH DFEFQWQEDK 120
RNSHEATMTQ IKKLTGSTDR YDRRHPGNKP IKDQLGLSFH SHLPELHIFQ TKGKVGNQVE 180
KSINDASSVL TSQRISSRPK IHISNNYENN FFHSSLLTLK QEVHIREKSF QCNESGKAFN 240
CSSLLRKHQI IYLGGKQYKC DVCGKVFNQK RYLACHHRCH TGEKPYKCNE CGKVFNQQSN 300
LASHHRLHTG EKPYKCEECD KVFSRKSNLE RHRRIHTGEK PYKCKVCEKA FRRDSHLTQH 360
TRIHTGEKPY KCNECGKAFS GQSTLIHHQA IHGIGKLYKC NDCHKVFSNA TTIANHWRIH 420
NEERSYKCNK CGKFFRRRSY LVVHWRTHTG EKPYKCNECG KTFHHNSALV IHKAIHTGEK 480
PYKCNECGKT FRHNSALVIH KAIHTGEKPY KCNECGKVFN QQATLARHHR LHTGEKPYKC 540
EECDTVFSRK SHHETHKRIH TGEKPYKCDD FDEAFSQASS YAKQRRIHMG EKHHKCDDCG 600
KAFTSHSHRI RHQRIHTGQK SYKCHKRGKV FS 632 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |