CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030883
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Exocyst complex component 7 
Protein Synonyms/Alias
 cDNA FLJ58532, highly similar to Exocyst complex component 7 
Gene Name
 EXOC7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
14SFESRLMKLENSIIPubiquitination[1]
24NSIIPVHKQTENLQRubiquitination[2]
77EYLGSMAKIQKAVEYubiquitination[3]
80GSMAKIQKAVEYFQDubiquitination[3]
97PDSPELNKVKLLFERubiquitination[3, 4]
99SPELNKVKLLFERGKubiquitination[3]
106KLLFERGKEALESEFubiquitination[3]
574DKERQIIKERFKGFNubiquitination[3]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 656 AA 
Protein Sequence
MVSILSSFES RLMKLENSII PVHKQTENLQ RLQENVEKTL SCLDHVISYY HVASDTEKII 60
REGPTGRLEE YLGSMAKIQK AVEYFQDNSP DSPELNKVKL LFERGKEALE SEFRSLMTRH 120
SKVVSPVLIL DLISGDDDLE AQEDVTLEHL PESVLQDVIR ISRWLVEYGR NQDFMNVYYQ 180
IRSSQLDRSI KGLKEHFHKS SSSSGVPYSP AIPNKRKDTP TKKPVKRPGT IRKAQNLLKQ 240
YSQHGLDGKK GGSNLIPLEG RDDMLDVETD AYIHCVSAFV KLAQSEYQLL ADIIPEHHQK 300
KTFDSLIQDA LDGLMLEGEN IVSAARKAIV RHDFSTVLTV FPILRHLKQT KPEFDQVLQG 360
TAASTKNKLP GLITSMETIG AKALEDFADN IKNDPDKEYN MPKDGTVHEL TSNAILFLQQ 420
LLDFQETAGA MLASQVLGDT YNIPLDPRET SSSATSYSSE FSKRLLSTYI CKVLGNLQLN 480
LLSKSKVYED PALSAIFLHN NYNYILKSLE KSELIQLVAV TQKTAERSYR EHIEQQIQTY 540
QRSWLKVTDY IAEKNLPVFQ PGVKLRDKER QIIKERFKGF NDGLEELCKI QKAWAIPDTE 600
QRDRIRQAQK TIVKETYGAF LQKFGSVPFT KNPEKYIKYG VEQVGDMIDR LFDTSA 656 
Gene Ontology
 GO:0000145; C:exocyst; IEA:InterPro.
 GO:0006887; P:exocytosis; IEA:InterPro. 
Interpro
 IPR016159; Cullin_repeat-like_dom.
 IPR004140; Exo70. 
Pfam
 PF03081; Exo70 
SMART
  
PROSITE
  
PRINTS