CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011303
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribonuclease H2 subunit B 
Protein Synonyms/Alias
 RNase H2 subunit B; Rnh2B; RNase H(202); Ribonuclease HI subunit B 
Gene Name
 RNH202 
Gene Synonyms/Alias
 YDR279W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
62IRSFQFGKGPSYSHEacetylation[1]
340KPKVAIGKGAIDGFFacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 350 AA 
Protein Sequence
MTVSNIGGEE RLIILPDDYE TSKTINTFTL PPPSNITSKP RIELFENING KLYEIRSFQF 60
GKGPSYSHEE DLANDKYHYT KENHPIKSTF IVNTSDPTDG YVFNSSKIHF CSLYDIAFSL 120
IGFYYRNSVS ADEQDYSNSS DTGENQKSNS KTNEKFLTVR DYHDFLTDNH DKNWENISLS 180
RLKSGLAKVS ETIEEAGDVY YKITSAMITQ FLLGKVSKIV ENFPPSIPTL KNAPTEIKQC 240
YKVVMATNLL VSLIPRAAYH NLLTFSPTMD SGCLNPDIKA SFIELENYET TNELQNAERE 300
LLMKSAMNVG LNSNGRVSLP VKKVTKKIVQ NKKPKVAIGK GAIDGFFKRK 350 
Gene Ontology
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0032299; C:ribonuclease H2 complex; IDA:SGD.
 GO:0043137; P:DNA replication, removal of RNA primer; IC:SGD. 
Interpro
 IPR019024; RNase_H2_suB. 
Pfam
 PF09468; RNase_H2-Ydr279 
SMART
  
PROSITE
  
PRINTS